{"id":"W4285495248","doi":"10.1080/15476286.2022.2096794","title":"Investigating the role of RNA structures in transcriptional pausing using in vitro assays and in silico analyses","year":2022,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; RNA; In silico; Transcription (linguistics); Genetics; Transcriptional regulation; Computational biology; DNA; Nucleic acid structure; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001376437,0.001384501,0.0009946228,0.0007504842,0.000486032,0.001628655,0.0008124664,0.001100736,0.001918753],"category_scores_gemma":[0.002294606,0.0004285762,0.001910985,0.0004288782,0.0004456407,0.001159069,0.000444004,0.001970808,0.001516242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007640094,"about_ca_system_score_gemma":0.0009224029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007269626,"about_ca_topic_score_gemma":0.001527576,"domain_scores_codex":[0.9992353,0.0002793965,0.00006284775,0.0001531723,0.0002118037,0.00005750713],"domain_scores_gemma":[0.9983619,0.0009658618,0.0002440184,0.0001719748,0.0001694946,0.00008681365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002532602,0.0002225984,0.004790839,0.0007041158,0.0001387239,0.0002526827,0.00007556913,0.0097739,0.9692616,0.002614249,0.0004069901,0.01150544],"study_design_scores_gemma":[0.00002429791,0.0003314633,0.004076207,0.00007875705,0.0002632403,0.0004548839,0.00009310095,0.0779209,0.9063846,0.002368255,0.007932648,0.00007163681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7096678,0.01203742,0.2608743,0.001446824,0.0005360775,0.0002655731,0.004050927,0.002361145,0.008759906],"genre_scores_gemma":[0.8923915,0.00403177,0.09408737,0.0003119428,0.00008902221,0.00009088829,0.006893374,0.0003256342,0.001778433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001918753,"threshold_uncertainty_score":0.007279396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03348542059811403,"score_gpt":0.2948927874555957,"score_spread":0.2614073668574816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}