{"id":"W4285606562","doi":"10.1016/j.ijrobp.2022.07.001","title":"Final Safety and Health-Related Quality of LIfe Results of the Phase 2/3 Act.In.Sarc Study With Preoperative NBTXR3 Plus Radiation Therapy Versus Radiation Therapy in Locally Advanced Soft-Tissue Sarcoma","year":2022,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eisai; Clovis Oncology; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Adverse effect; Trunk; Radiation therapy; Quality of life (healthcare); Population; Surgery; Soft tissue sarcoma; External beam radiation; Sarcoma; Soft tissue; Incidence (geometry); Nuclear medicine; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004727988,0.001581159,0.001915833,0.0003781315,0.0004135579,0.0007056029,0.0007753297,0.0009395261,0.003731206],"category_scores_gemma":[0.001483103,0.0005890226,0.002358921,0.0004179139,0.0008079931,0.0004708178,0.0004024315,0.001996827,0.0007401786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001100744,"about_ca_system_score_gemma":0.001907159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001844254,"about_ca_topic_score_gemma":0.006066564,"domain_scores_codex":[0.9980378,0.001534648,0.00005988131,0.0001031498,0.0001388267,0.000125769],"domain_scores_gemma":[0.9986609,0.00027531,0.0004776901,0.0001422424,0.0001246381,0.0003190915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9495518,0.01411416,0.005052206,0.0004553112,0.001949639,0.00004644245,0.00005487434,0.001053252,0.007332103,0.0001133144,0.003575333,0.01670155],"study_design_scores_gemma":[0.7052351,0.2587867,0.0265925,0.00006078804,0.002404335,0.00009134464,0.0000489782,0.001005257,0.002597089,0.0001675619,0.002982798,0.00002745192],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810795,0.002217562,0.001212972,0.0008343322,0.0002205633,0.003585695,0.006606072,0.0001061414,0.004137234],"genre_scores_gemma":[0.9724554,0.001925183,0.002765788,0.0018109,0.0003357648,0.005803308,0.009797524,0.00008573542,0.005020434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004727988,"threshold_uncertainty_score":0.02500427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05669756742817338,"score_gpt":0.3947065547257923,"score_spread":0.3380089872976189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}