{"id":"W4285679625","doi":"10.1016/j.jtct.2022.07.013","title":"Characteristics of Graft-Versus-Host Disease (GvHD) After Post-Transplantation Cyclophosphamide Versus Conventional GvHD Prophylaxis","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Defense Systems Management College; National Institute of Allergy and Infectious Diseases; Daiichi Sankyo Europe; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Pharmacyclics; Chugai Pharmaceutical; Merck Sharp and Dohme; U.S. Public Health Service; National Institutes of Health; Daiichi-Sankyo; Omeros Corporation; Astellas Pharma; Astellas Pharma US; Nippon Shinyaku; Incyte; Pfizer; CareDx; Plexxikon; Health Resources and Services Administration; Syndax Pharmaceuticals; Kyowa Kirin Pharmaceutical Development; Legend Biotech; CytoSen Therapeutics; Cancer Moonshot; Medical College of Wisconsin; Cidara Therapeutics; Novartis; Celgene; Moonshot Research and Development Program; Sanofi; Janssen Pharmaceuticals; Fuji Pharma; Merck; Bristol-Myers Squibb","keywords":"Medicine; Graft-versus-host disease; Internal medicine; Transplantation; Gastroenterology; Cyclophosphamide; Hazard ratio; Retrospective cohort study; Immunology; Surgery; Chemotherapy; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002515759,0.000281754,0.0003561178,0.000194449,0.0001991782,0.00002243334,0.00009902797,0.00008502694,0.00310055],"category_scores_gemma":[0.000007220333,0.000286119,0.0001828691,0.0002432442,0.0001318456,0.0001352162,0.000006870749,0.0002513079,0.00001687119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005912843,"about_ca_system_score_gemma":0.0001624544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003916076,"about_ca_topic_score_gemma":0.000006186838,"domain_scores_codex":[0.9978565,0.000170751,0.0005810096,0.0004114646,0.0007116429,0.0002686144],"domain_scores_gemma":[0.9990267,0.0001824083,0.0001859285,0.0002299309,0.0001487246,0.0002263293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4687872,0.003302002,0.2102637,0.01075261,0.00158829,0.00514795,0.02455236,0.00009605297,0.2275773,0.005388387,0.00003735154,0.04250687],"study_design_scores_gemma":[0.02660466,0.002388916,0.9271567,0.00008898013,0.0008319323,0.0001102026,0.0005868706,0.00008682427,0.04072117,0.00005654073,0.0008506743,0.0005165178],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926603,0.00104699,0.002455706,0.0002281952,0.0008577144,0.0009133801,0.001142434,0.00007428665,0.000621027],"genre_scores_gemma":[0.9907331,0.004592728,0.0003054204,0.0001926954,0.00005774052,0.0002111792,0.003691138,0.00004912521,0.0001668231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.716893,"threshold_uncertainty_score":0.9999591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01432678059424721,"score_gpt":0.2437695142646835,"score_spread":0.2294427336704362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}