{"id":"W4285731053","doi":"10.1038/s41375-022-01641-x","title":"PARP14 is a novel target in STAT6 mutant follicular lymphoma","year":2022,"lang":"en","type":"article","venue":"Leukemia","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; Deutschen Konsortium für Translationale Krebsforschung; Else Kröner-Fresenius-Stiftung; Deutsche Forschungsgemeinschaft; Deutsche Krebshilfe; Amgen","keywords":"Biology; Chromatin immunoprecipitation; Transactivation; Follicular lymphoma; Downregulation and upregulation; Molecular biology; Cell biology; Gene expression; Cancer research; Promoter; Lymphoma; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001641723,0.0001246431,0.00016995,0.0001248422,0.0002142343,0.000009524061,0.0001508379,0.00009239912,0.01337297],"category_scores_gemma":[0.00002001585,0.0001275192,0.00008851955,0.0001782622,0.00003491393,0.00008056802,0.0001168247,0.0002945689,0.0008469427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007303715,"about_ca_system_score_gemma":0.0001541822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005953527,"about_ca_topic_score_gemma":0.000007643258,"domain_scores_codex":[0.9990696,0.0001066303,0.0002516871,0.000250461,0.00004328316,0.0002783807],"domain_scores_gemma":[0.9996241,0.0000364367,0.00008221853,0.000224182,0.00002121965,0.00001179321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001014679,0.00033649,0.001244077,0.000009461769,0.0001183333,0.0000271303,0.001851244,0.0004829623,0.90951,0.0007877397,0.08269881,0.001919053],"study_design_scores_gemma":[0.005244944,0.0001493268,0.002542577,0.000006220267,0.00001014084,0.0001528807,0.000891612,0.000259598,0.08031943,0.00006887053,0.9101812,0.0001732154],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885932,0.0009329556,0.000390713,0.0003491594,0.004320646,0.0002633914,0.00002396263,0.00008126996,0.005044723],"genre_scores_gemma":[0.9734277,0.0000206886,0.00005115478,0.00189704,0.00001846872,0.0001169173,0.0001832882,0.0000173402,0.02426747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8291906,"threshold_uncertainty_score":0.999931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009853362402010126,"score_gpt":0.2172367335784208,"score_spread":0.2073833711764107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}