{"id":"W4285732868","doi":"10.3390/cells11142216","title":"BMP Signaling Pathway in Dentin Development and Diseases","year":2022,"lang":"en","type":"review","venue":"Cells","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"SMAD; Cell biology; RUNX2; Odontoblast; Signal transduction; Dentin sialophosphoprotein; Dentinogenesis; Bone morphogenetic protein 2; Bone morphogenetic protein; BMPR2; Biology; Chemistry; Dentin; Transcription factor; Medicine; Genetics; Dentistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001006847,0.0002267535,0.0003866212,0.00007912877,0.00006722128,0.00003533215,0.0001634981,0.0001011786,0.0001241983],"category_scores_gemma":[0.00000974421,0.000209774,0.00009790001,0.00008419107,0.00002723806,0.000001752604,0.0003351916,0.00009239541,0.00002405633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002830999,"about_ca_system_score_gemma":0.0002070322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001108689,"about_ca_topic_score_gemma":0.000005537976,"domain_scores_codex":[0.9990041,0.00005800828,0.000290535,0.0003548925,0.0001021293,0.0001903266],"domain_scores_gemma":[0.9997059,0.00001573127,0.000094036,0.000121263,0.000005093541,0.00005803357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003673501,0.00005404855,0.0001247984,0.002816263,0.00005713464,0.00005486812,0.0000515083,3.845904e-7,0.0005422487,0.000007470534,0.0003473581,0.9959403],"study_design_scores_gemma":[0.00009029922,0.00001346568,0.00001757172,0.0005504641,0.00002351987,0.000007325885,0.00003419807,6.347012e-8,0.00374525,0.000003061232,0.9952362,0.0002786162],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005761827,0.9932116,0.000003401663,9.392969e-7,0.0001988384,0.0002122978,0.000023094,0.000006631708,0.0005813572],"genre_scores_gemma":[0.0002446741,0.9942928,0.0001896073,0.00002842513,0.00006319688,0.00009933308,0.0007542142,0.00003056269,0.004297219],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9956616,"threshold_uncertainty_score":0.8554336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02395217363672578,"score_gpt":0.257085471297083,"score_spread":0.2331332976603572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}