{"id":"W4285732868","doi":"10.3390/cells11142216","title":"BMP Signaling Pathway in Dentin Development and Diseases","year":2022,"lang":"en","type":"review","venue":"Cells","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"SMAD; Cell biology; RUNX2; Odontoblast; Signal transduction; Dentin sialophosphoprotein; Dentinogenesis; Bone morphogenetic protein 2; Bone morphogenetic protein; BMPR2; Biology; Chemistry; Dentin; Transcription factor; Medicine; Genetics; Dentistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002342421,0.0005244291,0.0005990355,0.0008711096,0.0004519737,0.0008994936,0.0004528649,0.0007568456,0.005537795],"category_scores_gemma":[0.0002359301,0.0001327419,0.0002987313,0.001038672,0.0003571454,0.0004885701,0.0006458539,0.001201351,0.002887533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000523565,"about_ca_system_score_gemma":0.0009459151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009498431,"about_ca_topic_score_gemma":0.0008195333,"domain_scores_codex":[0.9997948,0.00003277827,0.00002297603,0.00003445642,0.00008775775,0.0000273265],"domain_scores_gemma":[0.9999353,0.00001238463,0.00001154825,0.000002962286,0.0000253147,0.00001250104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004094732,0.0001174298,0.001562122,0.01062214,0.000141626,0.003616584,0.0003699649,0.0006826773,0.06231152,0.03852691,0.08171627,0.7999234],"study_design_scores_gemma":[0.00001902356,0.00004887604,0.001706928,0.0009153694,0.00008143339,0.004937899,0.0001093398,0.0001432955,0.006419151,0.006791157,0.9788117,0.00001582519],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002220263,0.9796655,0.001544923,0.001362788,0.0009117635,0.0000215407,0.0002279768,0.00005258834,0.01399282],"genre_scores_gemma":[0.02794577,0.951866,0.002564132,0.001165999,0.000830299,0.00005254998,0.0004443416,0.00002778949,0.01510311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005537795,"threshold_uncertainty_score":0.01852584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02395217363672578,"score_gpt":0.257085471297083,"score_spread":0.2331332976603572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}