{"id":"W4285807313","doi":"10.1016/j.bbrc.2022.07.062","title":"Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance","year":2022,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Tenotomy; Calcineurin; Soleus muscle; Endocrinology; Internal medicine; Chemistry; Skeletal muscle; Sarcopenia; Myosin; Tendon; Biochemistry; Biology; Anatomy; Medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003908939,0.000647821,0.0005443733,0.0005485331,0.0004853552,0.0006256168,0.0006253136,0.0006917482,0.002339768],"category_scores_gemma":[0.0002686308,0.0004105892,0.0004074779,0.0002777946,0.001185471,0.0004648174,0.000453278,0.001156551,0.000646593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006570181,"about_ca_system_score_gemma":0.0005934801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001749024,"about_ca_topic_score_gemma":0.005841544,"domain_scores_codex":[0.9994919,0.00007146315,0.00008355288,0.0001329257,0.0001169024,0.0001032799],"domain_scores_gemma":[0.9993944,0.00009414656,0.0001975825,0.00007842136,0.00004288947,0.0001925912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003549696,0.00005621987,0.00008124781,0.0000280085,0.000008330048,0.00005465874,0.00003410324,0.00009494647,0.9986727,0.000151447,0.00004684087,0.0004165152],"study_design_scores_gemma":[0.00009773525,0.0003390171,0.002099267,0.00000790081,0.00003719379,0.0001614886,0.00008483648,0.0009765378,0.9945898,0.00005390375,0.001544053,0.000008248681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940241,0.0006145003,0.002521421,0.0003485178,0.00008934947,0.00004605989,0.0007916597,0.0002022002,0.001362253],"genre_scores_gemma":[0.9863296,0.0005331223,0.003758061,0.0001554666,0.00002367461,0.000131751,0.0006570794,0.0002132588,0.008198033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002339768,"threshold_uncertainty_score":0.007827342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04258103706686648,"score_gpt":0.3444239175020622,"score_spread":0.3018428804351957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}