{"id":"W4286110847","doi":"10.1021/acssynbio.2c00160","title":"Malarial Antibody Detection with an Engineered Yeast Agglutination Assay","year":2022,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto","funders":"Philippine Council for Health Research and Development; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Grand Challenges Canada","keywords":"Malaria; Agglutination (biology); Plasmodium falciparum; Antibody; Biology; Parasitemia; Yeast; Microbiology; Virology; Antigen; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002990348,0.0005812376,0.0002753673,0.0004165634,0.0001470701,0.0004387303,0.0004391971,0.0004354452,0.0005381235],"category_scores_gemma":[0.0003034264,0.0002463552,0.0002581235,0.0002862582,0.0001763008,0.0001491624,0.0003332924,0.000426491,0.0003503185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002478257,"about_ca_system_score_gemma":0.000159884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005070698,"about_ca_topic_score_gemma":0.0006837418,"domain_scores_codex":[0.9995313,0.0001169653,0.00004071701,0.0001048265,0.0001545346,0.00005166243],"domain_scores_gemma":[0.9997956,0.00003338656,0.00005946527,0.00002401631,0.00005748179,0.00003008401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003503679,0.00002533057,0.0003260433,0.00002395263,0.000006721695,0.00002404085,0.000008416177,0.00009478861,0.9980939,0.00004759666,0.00003451149,0.001279791],"study_design_scores_gemma":[0.000009205964,0.0002456084,0.002473179,0.000004291153,0.00001407361,0.0002022595,0.000009433791,0.004176793,0.9916942,0.000027315,0.001134162,0.000009479731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8476139,0.0008010163,0.1468298,0.00009867003,0.00006055809,0.0002238984,0.0006211734,0.001069645,0.00268131],"genre_scores_gemma":[0.8809961,0.0006294486,0.1144958,0.00008811463,0.00001541399,0.000136392,0.0007914152,0.00004109792,0.00280624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005812376,"threshold_uncertainty_score":0.001800179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006313200650389466,"score_gpt":0.2502778060771949,"score_spread":0.2439646054268055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}