{"id":"W4286268686","doi":"10.1016/j.redox.2022.102417","title":"Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis","year":2022,"lang":"en","type":"article","venue":"Redox Biology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"National Cancer Institute; National Institutes of Health; Cancer Prevention and Research Institute of Texas; American Cancer Society; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Colitis; Inflammation; Azoxymethane; Cancer research; Cytokine; Medicine; Bone marrow; Immunology; Carcinogenesis; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005519735,0.000198398,0.0003880672,0.0001571795,0.0001065341,0.000003819129,0.0003098846,0.0002747002,0.0001137608],"category_scores_gemma":[0.0002051582,0.0002139172,0.0001175012,0.0002622309,0.0002107295,0.000002094401,0.0004196755,0.0001818946,0.000004012254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001003765,"about_ca_system_score_gemma":0.0001542963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002816538,"about_ca_topic_score_gemma":0.0002351525,"domain_scores_codex":[0.9976658,0.0008065562,0.0004892476,0.0005132983,0.00009423967,0.0004308643],"domain_scores_gemma":[0.999113,0.00006748519,0.0002669074,0.0003937524,0.0001017061,0.00005715264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003011741,0.0002070866,0.01996329,0.00001351484,0.00005166221,0.00001924511,0.00007567761,0.00007984773,0.9781851,0.0002002649,0.0003205637,0.0005826342],"study_design_scores_gemma":[0.00196444,0.002029592,0.02166682,0.0000106854,0.00002680862,0.0001074949,0.0002723032,0.0001347426,0.9633231,0.0009990489,0.009060339,0.0004045985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971997,0.001248936,0.00007167502,0.0001776227,0.0003860848,0.000339609,0.0002559633,0.00002064935,0.0002997275],"genre_scores_gemma":[0.9977885,0.0001584479,0.0004128695,0.0001923852,0.00006898541,0.000145307,0.001078774,0.00002771801,0.0001269444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01486191,"threshold_uncertainty_score":0.8723288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009885671523180007,"score_gpt":0.2394026374475159,"score_spread":0.2295169659243359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}