{"id":"W4286294352","doi":"10.1200/jco.2022.40.16_suppl.e19062","title":"Clinical outcomes associated with azacitidine (AZA) monotherapy for treatment-naïve, higher-risk myelodysplastic syndrome (HR-MDS): A systematic literature review and meta-analysis.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Gilead Sciences","keywords":"Medicine; Internal medicine; Meta-analysis; Observational study; Retrospective cohort study; Randomized controlled trial; Prospective cohort study; Relative risk; Myelodysplastic syndromes; Oncology; Confidence interval; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01099563,0.002101695,0.01352093,0.007960414,0.0005291931,0.002635049,0.001638174,0.001856403,0.003421189],"category_scores_gemma":[0.02184352,0.001046258,0.02776906,0.008345903,0.0005596824,0.001604811,0.001315957,0.001424668,0.0003005043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002091163,"about_ca_system_score_gemma":0.003354182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004481104,"about_ca_topic_score_gemma":0.01174148,"domain_scores_codex":[0.9937679,0.002563941,0.002113099,0.0006724428,0.0006884405,0.0001943099],"domain_scores_gemma":[0.9827322,0.01207514,0.00353955,0.0003633171,0.001064382,0.0002253432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00195073,0.0000388347,0.004694587,0.541061,0.4352993,0.0001163465,0.00009404099,0.000364084,0.0002367944,0.0001262484,0.0006212764,0.01539675],"study_design_scores_gemma":[0.0004827035,0.0002554002,0.005090951,0.04063883,0.9511009,0.0001016075,0.00006055904,0.0001397861,0.00009933789,0.0001619368,0.001843587,0.0000244159],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.004229938,0.9943358,0.0002664914,0.000170614,0.00008149626,0.0002075291,0.0005214987,0.0000116438,0.000174868],"genre_scores_gemma":[0.1312116,0.8640667,0.001557678,0.0007104445,0.0002195229,0.0009685885,0.001023933,0.0000171174,0.0002245736],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01352093,"threshold_uncertainty_score":0.05815113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1736590505472295,"score_gpt":0.4826629651803021,"score_spread":0.3090039146330725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}