{"id":"W4286294884","doi":"10.1200/jco.2022.40.16_suppl.7042","title":"Hematologic improvements with ivosidenib + azacitidine compared to placebo + azacitidine in patients with newly diagnosed acute myeloid leukemia.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Myeloid leukemia; Azacitidine; Gastroenterology; Internal medicine; Placebo; Bone marrow; Population; Platelet; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006090358,0.0003888167,0.00134369,0.0002195764,0.000158398,0.0004045146,0.0002728293,0.0004310045,0.002677647],"category_scores_gemma":[0.0008561919,0.0001967491,0.0005875648,0.0002787683,0.0002722109,0.0002895948,0.0002208764,0.000954845,0.0002525045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003232802,"about_ca_system_score_gemma":0.0003611066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003922511,"about_ca_topic_score_gemma":0.001275847,"domain_scores_codex":[0.9997765,0.0001092364,0.00002047513,0.0000341437,0.00002522008,0.00003427586],"domain_scores_gemma":[0.9996879,0.0000860382,0.00009151088,0.00001528647,0.00001158351,0.0001076441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7555411,0.008641712,0.01274346,0.001062186,0.001500681,0.0001906964,0.0001692768,0.0009322313,0.0289452,0.0001258657,0.001682706,0.1884649],"study_design_scores_gemma":[0.3360791,0.5350831,0.1150471,0.0001592442,0.002480021,0.0005756454,0.0001010164,0.0009296527,0.004489157,0.000213845,0.004813115,0.0000290221],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918841,0.006446303,0.00008528495,0.0001941388,0.00008794822,0.000176677,0.0002223203,0.00002354403,0.0008797726],"genre_scores_gemma":[0.9960929,0.002051172,0.0003017441,0.0002733353,0.0001243434,0.0001815497,0.0003875544,0.000004737996,0.0005827043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002677647,"threshold_uncertainty_score":0.008957624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05185352637567781,"score_gpt":0.3877701962840926,"score_spread":0.3359166699084148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}