{"id":"W4286295522","doi":"10.1200/jco.2022.40.16_suppl.4559","title":"Avelumab first-line (1L) maintenance for advanced urothelial carcinoma (aUC): Long-term outcomes from JAVELIN Bladder 100 in subgroups defined by response to 1L chemotherapy.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Pfizer","keywords":"Medicine; Avelumab; Metastatic Urothelial Carcinoma; Internal medicine; Chemotherapy; Carboplatin; Gemcitabine; Oncology; Progressive disease; Chemotherapy regimen; Neutropenia; Bladder cancer; Gastroenterology; Cisplatin; Urothelial carcinoma; Pembrolizumab; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001412187,0.0003321733,0.000791311,0.000236624,0.000291641,0.0007057667,0.0003631571,0.0004988439,0.001685037],"category_scores_gemma":[0.0008776501,0.0001883857,0.001283343,0.0003353386,0.0003860829,0.0005772318,0.0004381897,0.001311598,0.0002765768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006953676,"about_ca_system_score_gemma":0.0007234397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00067044,"about_ca_topic_score_gemma":0.002177388,"domain_scores_codex":[0.9996004,0.0001660478,0.00002796184,0.00007631619,0.00004450614,0.00008491104],"domain_scores_gemma":[0.9992505,0.0001158852,0.0002249825,0.00005986186,0.00002886347,0.0003198613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6966354,0.01581913,0.1425054,0.000981361,0.003965456,0.0001932995,0.0002820679,0.002133241,0.01764939,0.0001939724,0.003533547,0.1161079],"study_design_scores_gemma":[0.1231141,0.4160688,0.4409113,0.0002150477,0.004293105,0.0007181522,0.0002082607,0.003021475,0.005121056,0.0005081795,0.005749552,0.00007101124],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968604,0.001569315,0.0001147545,0.0001128699,0.0000222683,0.0001681588,0.0006076985,0.00001199264,0.0005325767],"genre_scores_gemma":[0.9972651,0.0004591651,0.0001661906,0.0001747158,0.00003306231,0.0001790756,0.001310245,0.000004068997,0.0004083544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001685037,"threshold_uncertainty_score":0.007468402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08168948695276965,"score_gpt":0.41989050533008,"score_spread":0.3382010183773104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}