{"id":"W4286296857","doi":"10.1200/jco.2022.40.16_suppl.5084","title":"Patient (pt) population and radiation therapy (RT) type in the long-term phase 3 double-blind, placebo (PBO)-controlled ATLAS study of apalutamide (APA) added to androgen deprivation therapy (ADT) in high-risk localized or locally advanced prostate cancer (HRLPC).","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Janssen Research and Development","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Clinical endpoint; Population; Internal medicine; Bicalutamide; Urology; Oncology; Goserelin; Radiation therapy; Hormonal therapy; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002712723,0.001008227,0.001655202,0.0004195357,0.0003984226,0.0008152371,0.0006607141,0.001228876,0.00778648],"category_scores_gemma":[0.001413035,0.0004048794,0.001072523,0.0004417167,0.0010098,0.0006064302,0.0004060285,0.001994152,0.0009686167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005410077,"about_ca_system_score_gemma":0.001445288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004835457,"about_ca_topic_score_gemma":0.001404208,"domain_scores_codex":[0.9986112,0.0008065052,0.00009131979,0.0002171988,0.0001120467,0.0001617462],"domain_scores_gemma":[0.9992983,0.000162763,0.0001437703,0.00008582491,0.00004511472,0.0002641625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9674824,0.01337556,0.001623056,0.000211125,0.0004557439,0.00002609631,0.0000359651,0.0002819932,0.006462036,0.00007457758,0.0006600384,0.009311315],"study_design_scores_gemma":[0.6242052,0.3545378,0.01471795,0.00003180454,0.0009818814,0.00008141425,0.00004520513,0.0006169588,0.002690027,0.0002430722,0.001817923,0.00003078139],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869027,0.001777161,0.0008290087,0.0002402088,0.0002791863,0.006285479,0.001219362,0.0001160977,0.002350825],"genre_scores_gemma":[0.9842031,0.0006421235,0.00191709,0.0007695731,0.0002240863,0.008602175,0.0007981656,0.00002643361,0.002817292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00778648,"threshold_uncertainty_score":0.02604836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.102101994173479,"score_gpt":0.47783163263754,"score_spread":0.375729638464061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}