{"id":"W4286309149","doi":"10.1055/s-0042-1746281","title":"Once-Weekly Basal Insulin Icodec Offers Comparable Efficacy and Safety vs. Once-Daily Insulin Glargine U100 in Insulin-Naïve Patients with T2D Inadequately Controlled on OADS","year":2022,"lang":"en","type":"article","venue":"Diabetologie und Stoffwechsel","topic":"Diabetes Management and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"LMC Diabetes & Endocrinology (Canada)","funders":"","keywords":"Medicine; Insulin glargine; Insulin; Internal medicine; Hypoglycemia; Basal (medicine); Regular insulin; Endocrinology; Clinical endpoint; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001558993,0.000722523,0.002008705,0.00107353,0.000531271,0.0001145739,0.0006795125,0.0002565692,0.000293404],"category_scores_gemma":[0.0008268194,0.0005736237,0.0001683225,0.001596,0.0005083104,0.000243855,0.0006571658,0.00178297,0.00009023358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007922295,"about_ca_system_score_gemma":0.0004571241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534673,"about_ca_topic_score_gemma":0.00005666684,"domain_scores_codex":[0.9939214,0.0006938609,0.001085649,0.001222007,0.001590871,0.001486238],"domain_scores_gemma":[0.9968548,0.001231243,0.0003763236,0.0008446082,0.0002542736,0.00043879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.104592,0.01460703,0.7435574,0.0005811499,0.001846435,0.0007041068,0.001339483,0.006001896,0.0002040142,0.002067354,0.006797241,0.1177019],"study_design_scores_gemma":[0.1273707,0.01157273,0.8306208,0.0003104796,0.0003358946,0.00000160988,0.0005088961,0.006894448,0.0001944915,0.0003149257,0.02092632,0.0009487145],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837402,0.001467229,0.00004375268,0.003759523,0.0003599311,0.003950112,0.0001304408,0.0002231022,0.006325689],"genre_scores_gemma":[0.9942504,0.0003672507,0.0003642039,0.002060445,0.00008143699,0.0004309335,0.0005778912,0.0001000046,0.00176742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1167532,"threshold_uncertainty_score":0.9996715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0232475760854094,"score_gpt":0.280217230275101,"score_spread":0.2569696541896916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}