{"id":"W4286434092","doi":"10.3390/antiox11071416","title":"Inhibition of Cell Proliferation and Cell Viability by Sinecatechins in Cutaneous SCC Cells Is Related to an Imbalance of ROS and Loss of Mitochondrial Membrane Potential","year":2022,"lang":"en","type":"article","venue":"Antioxidants","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Elgin St. Thomas Community Foundation","keywords":"Viability assay; Apoptosis; Reactive oxygen species; Programmed cell death; Cell growth; Cell biology; Caspase; Biology; Cell; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010342,0.000318488,0.0002716336,0.0003014475,0.0001514977,0.0001932279,0.000109769,0.0002543469,0.001123487],"category_scores_gemma":[0.0001139263,0.00009305929,0.0002500523,0.0002690807,0.0001890136,0.0001734904,0.0001542202,0.00049788,0.0002185213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001493637,"about_ca_system_score_gemma":0.0001511828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005206473,"about_ca_topic_score_gemma":0.0009511237,"domain_scores_codex":[0.9998715,0.00002635133,0.00001792728,0.00002460124,0.00003801379,0.00002166357],"domain_scores_gemma":[0.999893,0.00003945229,0.00001994047,0.00001921591,0.00001858813,0.000009888465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006409713,0.00002914955,0.0002110326,0.00004963288,0.000003676741,0.00004579958,0.00001858633,0.00003337919,0.9976028,0.00002364669,0.00001407858,0.001904238],"study_design_scores_gemma":[0.000006493241,0.0003695205,0.005300219,0.000004919521,0.000009971739,0.0001395058,0.00002989798,0.0002980433,0.9930446,0.00002607927,0.0007686778,0.000002069307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930924,0.003183334,0.001882588,0.000071356,0.00002937978,0.00003758007,0.0002172027,0.00004991434,0.001436211],"genre_scores_gemma":[0.9959815,0.001128998,0.001037663,0.00002283047,0.000006656604,0.00003812083,0.0002614818,0.000006098652,0.001516659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001123487,"threshold_uncertainty_score":0.00375843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003797545309181288,"score_gpt":0.2167514824425213,"score_spread":0.21295393713334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}