{"id":"W4286449404","doi":"10.1016/j.peptides.2022.170844","title":"PCP consensus protein/peptide alphavirus antigens stimulate broad spectrum neutralizing antibodies","year":2022,"lang":"en","type":"article","venue":"Peptides","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Laboratory Directed Research and Development; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Alphavirus; Virology; Antigen; Biology; Antibody; Chikungunya; Venezuelan equine encephalitis virus; Immunogenicity; Neutralization; Serotype; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004287568,0.000724339,0.000257679,0.0003619957,0.0001777858,0.0004045423,0.0002122906,0.0005488307,0.005420867],"category_scores_gemma":[0.0005227231,0.0002214992,0.0003234254,0.0001484016,0.0001791958,0.0002447988,0.0003565105,0.001430155,0.0008933512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002816853,"about_ca_system_score_gemma":0.0002546883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005484478,"about_ca_topic_score_gemma":0.0006104567,"domain_scores_codex":[0.9994969,0.0001457334,0.00001561734,0.00004345072,0.00008132611,0.0002168299],"domain_scores_gemma":[0.9995757,0.0002363191,0.0000260873,0.00003174371,0.0000459088,0.0000842314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001445262,0.0007485794,0.0008269405,0.0001190588,0.00002265548,0.0002352821,0.00006614417,0.0004983189,0.9862045,0.0004090234,0.0005036112,0.008920696],"study_design_scores_gemma":[0.0008527056,0.01137027,0.02925171,0.00006127191,0.00008349709,0.001424691,0.0003238658,0.006181001,0.9425275,0.0007411254,0.007163754,0.00001870929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890097,0.0005867307,0.001225235,0.00008654384,0.0001497431,0.0001037466,0.0001037264,0.00003692706,0.008697608],"genre_scores_gemma":[0.9948744,0.0003149909,0.0005198785,0.0001481464,0.00008987948,0.00003046611,0.000181921,0.00001033142,0.003830055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005420867,"threshold_uncertainty_score":0.01813459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02083787987616582,"score_gpt":0.2798790859661609,"score_spread":0.2590412060899951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}