{"id":"W4286491054","doi":"10.1101/2022.07.20.500468","title":"Drosophila immune priming to Enterococcus faecalis relies on immune tolerance rather than resistance","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University; National Institutes of Health; National Science Foundation","keywords":"Immune system; Biology; Priming (agriculture); Drosophila melanogaster; Immunity; Innate immune system; Microbiology; Immunology; Acquired immune system; Transcriptome; Gene; Genetics; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.001497239,0.00131869,0.001592469,0.0007254285,0.0009526005,0.0002188161,0.002200912,0.0009475574,0.0009710565],"category_scores_gemma":[0.0004214214,0.001449426,0.0005429963,0.0007598327,0.0002691686,0.0001650195,0.002153744,0.002726248,0.001379616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009118322,"about_ca_system_score_gemma":0.0006040994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001616712,"about_ca_topic_score_gemma":0.000009628885,"domain_scores_codex":[0.9935215,0.001188073,0.00141887,0.002077198,0.0003307412,0.001463576],"domain_scores_gemma":[0.9947333,0.0002354812,0.0009110634,0.003589989,0.0003909655,0.0001391947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001369829,0.0003384033,0.0002000511,0.0002306214,0.000455024,0.0001224427,0.0001564688,0.0001187547,0.9931249,0.002824703,0.001055315,0.000003455491],"study_design_scores_gemma":[0.001337382,0.0002638742,0.01476405,0.001033202,0.0001270943,1.433452e-7,0.00003186315,0.000008478815,0.9051875,0.00001119282,0.07577924,0.001455949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715536,0.01479884,0.0004891688,0.001190013,0.00775843,0.002382998,0.0007544559,0.0009492153,0.0001233109],"genre_scores_gemma":[0.9945542,0.0004143925,0.001102567,0.000913671,0.0001997931,0.001374713,0.000006937977,0.0003854953,0.001048225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08793741,"threshold_uncertainty_score":0.9999564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185542575000586,"score_gpt":0.2164365578121393,"score_spread":0.2045811320621335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}