{"id":"W4286491054","doi":"10.1101/2022.07.20.500468","title":"Drosophila immune priming to Enterococcus faecalis relies on immune tolerance rather than resistance","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University; National Institutes of Health; National Science Foundation","keywords":"Immune system; Biology; Priming (agriculture); Drosophila melanogaster; Immunity; Innate immune system; Microbiology; Immunology; Acquired immune system; Transcriptome; Gene; Genetics; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006556547,0.000303668,0.0001776121,0.0001825324,0.0001216164,0.00027074,0.00007805474,0.0001870839,0.001041092],"category_scores_gemma":[0.00006893377,0.0001155025,0.0001752939,0.0001039076,0.0001859343,0.0001496646,0.0002053451,0.0005116679,0.00047829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002714412,"about_ca_system_score_gemma":0.000124567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004092224,"about_ca_topic_score_gemma":0.0006018531,"domain_scores_codex":[0.9999192,0.000008216026,0.000005894486,0.00003017356,0.0000209217,0.00001560906],"domain_scores_gemma":[0.999918,0.00001624977,0.00002628421,0.00001207553,0.0000111431,0.00001622314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001880763,0.000003404749,0.0002576779,0.00001551522,9.714321e-7,0.00001369663,0.000004856901,0.00001682851,0.9992368,0.00002774825,0.00002599537,0.0003776948],"study_design_scores_gemma":[0.000006878446,0.00007095645,0.02939824,0.000009602956,0.000006984794,0.0001352945,0.00004297787,0.0006302003,0.9679785,0.00006626394,0.0016488,0.000005152691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902333,0.0007563964,0.004116908,0.000111473,0.00002486393,0.00002606175,0.002423358,0.0002025015,0.002105123],"genre_scores_gemma":[0.9893769,0.0003999413,0.003763915,0.0001357341,0.000007570618,0.00004094309,0.002017293,0.00006934352,0.00418835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001041092,"threshold_uncertainty_score":0.003482759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185542575000586,"score_gpt":0.2164365578121393,"score_spread":0.2045811320621335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}