{"id":"W4286502387","doi":"10.1002/mus.27680","title":"Thermoneutral Housing and a Western Diet Combination Exacerbates <scp>Dysferlin‐Deficient</scp> Muscular Dystrophy","year":2022,"lang":"en","type":"article","venue":"Muscle & Nerve","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; St. Paul's Hospital; University of British Columbia Hospital","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research; Jain Foundation","keywords":"Dysferlin; Internal medicine; Endocrinology; Muscular dystrophy; Wasting; Skeletal muscle; Biology; Matricellular protein; Gastrocnemius muscle; Protein kinase B; Blot; Phosphorylation; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002133639,0.0009468384,0.0007424208,0.0007401406,0.000370533,0.0004552495,0.0003831524,0.0004959754,0.003372585],"category_scores_gemma":[0.0001103707,0.0002940558,0.0005512349,0.000300984,0.000564336,0.0003672045,0.0006423512,0.001171105,0.0005092849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005123951,"about_ca_system_score_gemma":0.0003592659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001337468,"about_ca_topic_score_gemma":0.004086387,"domain_scores_codex":[0.999558,0.00004975293,0.00006348186,0.0001257122,0.0001195226,0.00008342288],"domain_scores_gemma":[0.9996979,0.00001385625,0.0001185616,0.00002037283,0.00002372421,0.0001255848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006038654,0.0001599093,0.0006404537,0.00007705317,0.00002321984,0.0001156567,0.0000209533,0.00002739365,0.9973659,0.00002304149,0.0001152702,0.0008273433],"study_design_scores_gemma":[0.0001793846,0.005767404,0.0746336,0.00009792219,0.0002285461,0.002214708,0.0002222053,0.0008458106,0.9098405,0.00008572775,0.005830054,0.00005416877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960501,0.0008697156,0.001001145,0.0001576783,0.00005418462,0.00006150148,0.0007967809,0.0001934913,0.0008154443],"genre_scores_gemma":[0.9896717,0.0009714828,0.003357056,0.0002765667,0.00003642437,0.0002493635,0.001586796,0.00008744755,0.003763071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003372585,"threshold_uncertainty_score":0.01128238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008784897922574399,"score_gpt":0.2175067339391972,"score_spread":0.2087218360166228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}