{"id":"W4286562305","doi":"10.3410/f.742159970.793594313","title":"Faculty Opinions recommendation of Inability to phosphorylate Y88 of p27Kip1 enforces reduced p27 protein levels and accelerates leukemia progression.","year":2022,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Phosphorylation; Leukemia; Cancer research; Computer science; Psychology; Computational biology; Cell biology; Biology; Chemistry; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008689922,0.001588143,0.001077231,0.001617875,0.0006347116,0.001867231,0.001639666,0.002269845,0.03086402],"category_scores_gemma":[0.003831757,0.0003651078,0.001464781,0.002453847,0.0003103453,0.0008006289,0.0009837581,0.001269639,0.02886839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001234883,"about_ca_system_score_gemma":0.002013592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02539869,"about_ca_topic_score_gemma":0.07008266,"domain_scores_codex":[0.9992757,0.0001070862,0.00005613843,0.0002589389,0.0001931811,0.0001089312],"domain_scores_gemma":[0.9986858,0.0003519781,0.0001628054,0.0002388782,0.0003376029,0.0002228863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003070644,0.0000716909,0.004758477,0.0008526131,0.0001333454,0.00005545964,0.00001567878,0.0005051086,0.000501735,0.0003224542,0.9864329,0.006043633],"study_design_scores_gemma":[0.0008762139,0.0001069712,0.02402547,0.0003802392,0.0002615557,0.0003306689,0.00009442498,0.002992908,0.002415928,0.001768458,0.9666864,0.00006071689],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.001462415,0.0003316363,0.0001151084,0.0003258988,0.0000729687,0.00001864858,0.9956031,0.0004160993,0.001654136],"genre_scores_gemma":[0.002886281,0.0001692714,0.0004523013,0.000172169,0.00001549078,0.00003878917,0.9946399,0.0000370987,0.001588565],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.03086402,"threshold_uncertainty_score":0.1032504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03786296856405798,"score_gpt":0.3720236041102932,"score_spread":0.3341606355462353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}