{"id":"W4286586215","doi":"10.1097/aln.0000000000004326","title":"No Benefits of Adding Dexmedetomidine, Ketamine, Dexamethasone, and Nerve Blocks to an Established Multimodal Analgesic Regimen after Total Knee Arthroplasty","year":2022,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Dexmedetomidine; Ketamine; Analgesic; Anesthesia; Regimen; Dexamethasone; Total knee arthroplasty; Arthroplasty; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007613025,0.0003002252,0.0006788046,0.0003548439,0.0001829281,0.00001494371,0.0001203209,0.000124704,0.0006095215],"category_scores_gemma":[0.0001564225,0.0002768841,0.0001056376,0.0003746596,0.0001389101,0.0001033971,0.0001714521,0.0003053783,0.00002096819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005138052,"about_ca_system_score_gemma":0.00006608393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002736488,"about_ca_topic_score_gemma":0.00003225076,"domain_scores_codex":[0.9977279,0.0004134179,0.0004354936,0.0006362394,0.0002961282,0.0004908558],"domain_scores_gemma":[0.9985443,0.0003525411,0.000157358,0.0005440383,0.000112557,0.0002892546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003400232,0.0005016727,0.9740831,0.0001252157,0.0001585867,0.0008598894,0.001291903,0.001663345,0.002035702,0.0003191053,0.002165037,0.01339622],"study_design_scores_gemma":[0.001175975,0.005317545,0.9723693,0.00004624761,0.0001829418,0.0007962188,0.0008083642,0.001076233,0.0002272026,0.00002565787,0.01763761,0.0003367534],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978531,0.0005815001,0.00001567993,0.0002900446,0.00008806137,0.0007188376,0.000007175665,0.00006738409,0.0003782304],"genre_scores_gemma":[0.9918933,0.00003058023,0.003415816,0.002313604,0.000179429,0.0002684322,0.00006581721,0.0000484396,0.001784582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01547258,"threshold_uncertainty_score":0.9999683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139591372463199,"score_gpt":0.2359764552989441,"score_spread":0.2245805415743121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}