{"id":"W4286587583","doi":"10.3390/cancers14153563","title":"The Effect of the Gut Microbiota on Systemic and Anti-Tumor Immunity and Response to Systemic Therapy against Cancer","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Weston Family Foundation","keywords":"Systemic therapy; Cancer; Immunity; Immunology; Medicine; Systemic antibiotics; Immune system; Biology; Internal medicine; Microbiology; Antibiotics; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009151864,0.0003496421,0.0007870947,0.00005280093,0.0004172806,0.00003080859,0.0004753013,0.0001635427,0.000004462112],"category_scores_gemma":[0.00008108804,0.0001892288,0.0002064794,0.0001782843,0.000165882,0.000001247275,0.0002536929,0.0003394365,0.000001089419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000579867,"about_ca_system_score_gemma":0.001294149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002330709,"about_ca_topic_score_gemma":0.00004475266,"domain_scores_codex":[0.9974406,0.001376911,0.0003737481,0.0004223009,0.0000965995,0.0002898576],"domain_scores_gemma":[0.9985462,0.0002257744,0.0003609718,0.0007604141,0.00002861572,0.00007805662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001339196,0.000007995036,0.0001407702,0.01644225,0.0005167488,0.00000400369,0.0002432321,0.00004197746,0.6643506,0.000003794368,0.004061028,0.3128484],"study_design_scores_gemma":[0.0004561991,0.0004925044,0.0001482106,0.005984795,0.0001119188,0.0001025083,0.00007854803,4.452126e-7,0.001293464,7.040057e-8,0.9910928,0.0002385188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3606971,0.6374142,1.496737e-7,0.00002790162,0.0003920409,0.001224146,0.0002229352,0.000003685471,0.00001783752],"genre_scores_gemma":[0.05251114,0.9465782,8.606187e-7,0.0002335818,0.00008335508,0.0003019654,0.00002599358,0.00004658887,0.0002182808],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9870318,"threshold_uncertainty_score":0.7716528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01678748419258271,"score_gpt":0.3135006488869134,"score_spread":0.2967131646943307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}