{"id":"W4286600159","doi":"10.1016/b978-0-323-89774-7.00026-1","title":"MicroRNA turnover and nuclear function","year":2022,"lang":"en","type":"book-chapter","venue":"MicroRNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"microRNA; Gene silencing; Cell biology; Biology; Dicer; Ran; Argonaute; Drosha; Biogenesis; Nuclear transport; Nuclear export signal; RNA interference; Gene expression; Cell nucleus; Gene; Genetics; RNA; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001118599,0.0002334674,0.0001842828,0.0000678623,0.0001652914,0.00004382011,0.000169604,0.0002539314,0.001654643],"category_scores_gemma":[0.0000114327,0.0002417007,0.0001228227,0.0000140603,0.0000883989,0.000002988094,0.0003606125,0.0003601713,0.00009869339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003349032,"about_ca_system_score_gemma":0.00005135977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002715803,"about_ca_topic_score_gemma":0.00002181537,"domain_scores_codex":[0.9989555,0.00001649624,0.0001655841,0.0004641691,0.0001526568,0.000245615],"domain_scores_gemma":[0.9994198,0.000005646139,0.00008851202,0.0003360775,0.00004067857,0.0001092561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000169767,0.000009073471,0.00001542672,0.00003051407,0.000118009,0.00001946561,0.00001404113,5.06501e-7,0.9450956,0.001973605,0.04791552,0.00463848],"study_design_scores_gemma":[0.0003265568,0.0002955179,0.00007516991,0.00001770352,0.00002964802,0.00006143636,0.00001048964,0.000002254693,0.003356229,0.0001793129,0.9953828,0.0002628379],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.2606145,0.01500185,0.00006439869,0.000604232,0.0006068102,0.0006013583,0.0002816586,0.00005485722,0.7221704],"genre_scores_gemma":[0.0400333,0.002109586,0.0001341767,0.0009877749,0.0005666086,0.000008088227,0.0004994841,0.0001526222,0.9555084],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.9474673,"threshold_uncertainty_score":0.999258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000947204629849,"score_gpt":0.2192110219905752,"score_spread":0.2092015499442767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}