{"id":"W4286600159","doi":"10.1016/b978-0-323-89774-7.00026-1","title":"MicroRNA turnover and nuclear function","year":2022,"lang":"en","type":"book-chapter","venue":"MicroRNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"microRNA; Gene silencing; Cell biology; Biology; Dicer; Ran; Argonaute; Drosha; Biogenesis; Nuclear transport; Nuclear export signal; RNA interference; Gene expression; Cell nucleus; Gene; Genetics; RNA; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002516418,0.0004213313,0.0004525608,0.0004124205,0.000527992,0.002057019,0.000587276,0.001004523,0.008209507],"category_scores_gemma":[0.0002590607,0.0003514471,0.0002142625,0.000475135,0.000795175,0.00171053,0.0006893281,0.001241002,0.006014952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008823982,"about_ca_system_score_gemma":0.0003454941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003365614,"about_ca_topic_score_gemma":0.0005837009,"domain_scores_codex":[0.9998701,0.00001667219,0.000005097276,0.00003804906,0.00005750307,0.00001264],"domain_scores_gemma":[0.999939,0.00002957226,0.000004348272,0.00001041921,0.000008543355,0.000008166786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001627123,0.00004326205,0.00009476898,0.0004531058,0.00001172269,0.000460891,0.0003155022,0.001126366,0.1550974,0.4633487,0.0459126,0.332973],"study_design_scores_gemma":[0.000007177828,0.00003975416,0.0003696349,0.0001023509,0.000008975504,0.001112251,0.0001418685,0.001175712,0.04901756,0.09643784,0.8515666,0.00002023728],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01510981,0.2972412,0.04944841,0.004142714,0.00319579,0.0000393357,0.0003120789,0.000808316,0.6297024],"genre_scores_gemma":[0.09869228,0.09533533,0.01285153,0.001544987,0.001002207,0.0001167337,0.0004874688,0.0004424173,0.7895271],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.008209507,"threshold_uncertainty_score":0.0274635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000947204629849,"score_gpt":0.2192110219905752,"score_spread":0.2092015499442767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}