{"id":"W4286716116","doi":"10.1101/2022.07.20.500906","title":"HfaE is a component of the holdfast anchor complex that tethers the holdfast adhesin to the cell envelope","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Holdfast; Bacterial adhesin; Cell biology; Mutant; Biology; Secretion; Chemistry; Biochemistry; Virulence; Botany; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007615969,0.0005765191,0.000277175,0.000275428,0.0002749062,0.0004224501,0.0002486076,0.0005313103,0.001748725],"category_scores_gemma":[0.0001575104,0.0001655689,0.0003764228,0.0002232052,0.0001380003,0.0003333153,0.0003077193,0.0003653263,0.0008545288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069039,"about_ca_system_score_gemma":0.0001295367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001778922,"about_ca_topic_score_gemma":0.0008985928,"domain_scores_codex":[0.9999217,0.000005362133,0.000005941004,0.00001763963,0.00003276292,0.00001658197],"domain_scores_gemma":[0.9998703,0.00001851942,0.00003471256,0.00001368294,0.00002442164,0.00003841466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004221952,0.00001486509,0.001132736,0.00002960466,0.00001126438,0.0001634558,0.00001602217,0.00006433634,0.9965531,0.00009551719,0.0001012901,0.001775711],"study_design_scores_gemma":[0.00001853432,0.0001540497,0.05464401,0.00001570288,0.00003510833,0.001280726,0.0001174848,0.003309861,0.9324104,0.0001305581,0.007864883,0.00001873398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892464,0.001016377,0.007707186,0.0001027717,0.00006565317,0.00002835427,0.0007810927,0.0002261129,0.0008259595],"genre_scores_gemma":[0.9837462,0.0004950265,0.006396241,0.0001000713,0.00002590697,0.00001631755,0.00324494,0.00004424198,0.005931091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001778922,"threshold_uncertainty_score":0.005850017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02088542153377687,"score_gpt":0.2174884387204348,"score_spread":0.1966030171866579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}