{"id":"W4286828302","doi":"10.17615/a85y-vk50","title":"In Vivo miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis","year":2022,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; University of Toronto; National Cancer Institute; Massachusetts General Hospital","keywords":"Decoy; microRNA; Suppressor; In vivo; Melanoma; Metastasis; Cancer research; Cancer; Medicine; Biology; Internal medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002147896,0.0001536317,0.0004082262,0.0003660557,0.0001031153,0.00003090191,0.0001753837,0.00004137182,0.01292172],"category_scores_gemma":[0.0001126921,0.0001461849,0.0001239925,0.0004475464,0.00007762689,0.0001906007,0.0003057519,0.0001849283,0.00003196208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005665588,"about_ca_system_score_gemma":0.00009079431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004178123,"about_ca_topic_score_gemma":0.00004829848,"domain_scores_codex":[0.9985714,0.0001250677,0.000390175,0.0002711727,0.0003976935,0.0002445099],"domain_scores_gemma":[0.9992516,0.0001168719,0.0001261295,0.0003778017,0.00002639496,0.0001011828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006458362,0.001882475,0.01646016,0.0007988644,0.001338948,0.003774823,0.00671879,0.0001166301,0.1153777,0.3306104,0.5102077,0.006255182],"study_design_scores_gemma":[0.003215609,0.001590428,0.002853028,0.00006644364,0.0002664709,0.0006434118,0.003472973,0.00009806784,0.1743033,0.02214007,0.7909957,0.0003545194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.921634,0.001168819,0.00009847914,0.007597288,0.0005515786,0.001129323,0.0002067899,0.0001626354,0.0674511],"genre_scores_gemma":[0.9478299,0.00001196536,0.004969283,0.002426687,0.00008713784,0.0001222171,0.00003536279,0.00004123182,0.04447623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3084704,"threshold_uncertainty_score":0.9879806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01740020557959476,"score_gpt":0.2492307285791641,"score_spread":0.2318305229995694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}