{"id":"W4287448127","doi":"10.1242/dev.200773","title":"Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney","year":2022,"lang":"en","type":"article","venue":"Development","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Biology; Nephron; Kidney development; Bone morphogenetic protein 7; Kidney; Cell biology; Endocrinology; Genetics; Gene; Bone morphogenetic protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001525102,0.00008970815,0.0000651224,0.00002184005,0.0001818069,0.00001466612,0.0001186748,0.00003815462,0.00001982591],"category_scores_gemma":[0.0000112496,0.00006325581,0.00001644704,0.00008244571,0.00002810022,0.000002567913,0.0001662046,0.00008768711,0.000003059228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003487257,"about_ca_system_score_gemma":0.0002278359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009222051,"about_ca_topic_score_gemma":0.0000121564,"domain_scores_codex":[0.999341,0.00005018757,0.0001336853,0.0001976688,0.0001251658,0.0001523106],"domain_scores_gemma":[0.9998314,0.000004697695,0.00003190054,0.00008699682,0.00001206303,0.00003290672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005313103,0.000304972,0.1261006,0.0002542903,0.0002702794,0.0002028493,0.02012989,0.0003711992,0.6587633,0.0005182939,0.0339026,0.1586504],"study_design_scores_gemma":[0.0008884234,0.0001006872,0.06324849,0.00004963628,0.000007931642,0.0001926634,0.001244623,0.00004562175,0.1198286,0.00009377932,0.8139201,0.0003794966],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980245,0.0002388925,0.00008677254,0.0007334711,0.0001063411,0.0001511796,0.000001593628,0.000005018395,0.0006522968],"genre_scores_gemma":[0.995228,0.0001456793,0.002258681,0.001607577,0.00004124819,0.0001466977,0.00005487792,0.000009190117,0.0005080847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7800174,"threshold_uncertainty_score":0.2579497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007395406415820742,"score_gpt":0.2312131201236623,"score_spread":0.2238177137078416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}