{"id":"W4287835825","doi":"10.3390/cancers14153613","title":"Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"National Institute on Minority Health and Health Disparities; National Cancer Institute; University of South Florida","keywords":"Cancer research; Immune system; Pancreatic cancer; microRNA; Tumor microenvironment; Myelopoiesis; miR-155; Apigenin; Biology; Medicine; Cancer; Immunology; Stem cell; Cell biology; Haematopoiesis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002397349,0.0001476679,0.0001957369,0.00007118264,0.0001834225,0.00001931543,0.0001767413,0.00003894249,0.0001840276],"category_scores_gemma":[0.00005591092,0.0001477817,0.0000410606,0.0001243514,0.00006619922,0.000006709047,0.0001622212,0.000115803,0.000001019203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001254312,"about_ca_system_score_gemma":0.0003582011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004584503,"about_ca_topic_score_gemma":0.00008412122,"domain_scores_codex":[0.9988526,0.0001344349,0.0001950231,0.0003905604,0.0001408573,0.0002865663],"domain_scores_gemma":[0.9996027,0.00001815434,0.00009191163,0.0001871499,0.0000227799,0.00007724996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002502665,0.000009653381,0.02261236,0.00002073234,0.00002094996,0.00001213604,0.0003345427,0.0005979419,0.9744428,0.000004573543,0.001340893,0.0003531236],"study_design_scores_gemma":[0.0009225397,0.00006927323,0.01163984,0.00003984452,0.00001918079,0.00001080041,0.0007353582,0.00005543018,0.9427738,0.00002424456,0.04345951,0.0002501875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715742,0.02755212,0.00004863892,0.00005097526,0.0004450632,0.0001677369,0.00007365562,0.000008990159,0.00007859954],"genre_scores_gemma":[0.9965548,0.001659016,0.0001735198,0.0005473002,0.0001946843,0.000251215,0.0000305206,0.00002208507,0.000566874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04211862,"threshold_uncertainty_score":0.6026363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137594413527403,"score_gpt":0.2650264873564633,"score_spread":0.2536505432211892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}