{"id":"W4287845207","doi":"10.1016/j.bone.2022.116505","title":"OSTM1 pleiotropic roles from osteopetrosis to neurodegeneration","year":2022,"lang":"en","type":"article","venue":"Bone","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Osteopetrosis; Disease; Neurodegeneration; Mutation; Genetics; Inherited disease; Genetic heterogeneity; Biology; Medicine; Gene; Pathology; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001907608,0.0007395211,0.0004485323,0.0005221111,0.0003562088,0.0004753969,0.0003381844,0.0005240823,0.003297656],"category_scores_gemma":[0.0002338897,0.0001575013,0.0002335909,0.0002767055,0.0005587935,0.0002068644,0.0009240998,0.0008479051,0.0007198759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004467219,"about_ca_system_score_gemma":0.0004345108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005863665,"about_ca_topic_score_gemma":0.00114472,"domain_scores_codex":[0.9998589,0.00002599006,0.000009794593,0.00002564536,0.00005736139,0.00002243898],"domain_scores_gemma":[0.9998831,0.00001427125,0.00003233631,0.000004891644,0.0000178011,0.00004765884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002600687,0.0001728343,0.02259084,0.002822003,0.0001352884,0.02887491,0.0006675554,0.0008457173,0.7011882,0.02742377,0.03783467,0.1748435],"study_design_scores_gemma":[0.0005337163,0.001408441,0.2109382,0.00192192,0.0003422207,0.1009132,0.0006770732,0.001290395,0.1772094,0.018166,0.4864423,0.0001571469],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5138972,0.4081964,0.009229415,0.01086691,0.001182268,0.0001595581,0.00528386,0.001088122,0.05009606],"genre_scores_gemma":[0.8324456,0.142711,0.005522162,0.001381494,0.0006643182,0.0001389336,0.002045878,0.00008714665,0.01500339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003297656,"threshold_uncertainty_score":0.01103175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005960734644476489,"score_gpt":0.2076702837279112,"score_spread":0.2017095490834347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}