{"id":"W4287904860","doi":"10.5281/zenodo.4668557","title":"Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Children's Hospital","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; European Commission","keywords":"Immunology; Chimeric antigen receptor; Antigen; Medicine; Receptor; Immunotherapy; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002715176,0.0004658911,0.0005053732,0.0003020571,0.0001067934,0.0002976288,0.0002663483,0.0003067094,0.001477777],"category_scores_gemma":[0.0001458489,0.0001203043,0.0002235515,0.00009227556,0.0001775554,0.0002325128,0.0001406097,0.0009686388,0.0004222749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001383132,"about_ca_system_score_gemma":0.0002394347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002076913,"about_ca_topic_score_gemma":0.0004022143,"domain_scores_codex":[0.9998036,0.00002722878,0.00001415934,0.00003619763,0.00006118913,0.00005767543],"domain_scores_gemma":[0.999872,0.00002279731,0.00003003084,0.00001792145,0.00001014458,0.00004710631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003804156,0.0004182705,0.0001549837,0.00003773935,0.000006827769,0.00003221384,0.00001329351,0.0001490953,0.9939299,0.0001514423,0.00007994351,0.004645766],"study_design_scores_gemma":[0.0002962101,0.005348337,0.003390997,0.00001403726,0.0000522776,0.0005625519,0.00002509977,0.002401286,0.9847466,0.0001660281,0.002987239,0.000009498429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919612,0.001567406,0.003859659,0.0000795831,0.00008709757,0.00006219764,0.0001213206,0.0002980252,0.001963491],"genre_scores_gemma":[0.9930087,0.0008296244,0.002143433,0.00008141194,0.00004779188,0.00005541502,0.0001809349,0.00004910519,0.003603607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001477777,"threshold_uncertainty_score":0.004943669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05432740647686941,"score_gpt":0.2621514890529884,"score_spread":0.207824082576119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}