{"id":"W4288049183","doi":"10.1017/s0022215122000846","title":"Establishment of four head and neck squamous cell carcinoma cell lines: importance of reference DNA for accurate genomic characterisation","year":2022,"lang":"en","type":"article","venue":"The Journal of Laryngology & Otology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Ontario Institute for Cancer Research","funders":"National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Government of Ontario; Ontario Institute for Cancer Research","keywords":"Exome sequencing; Cell culture; Medicine; DNA; Exome; DNA sequencing; DNA profiling; Cell; Human cell; Human papillomavirus; Cancer research; Mutation; Genetics; Biology; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001875098,0.0004130398,0.0007467093,0.0009528407,0.0005578458,0.0009761382,0.0006745411,0.000806485,0.001924528],"category_scores_gemma":[0.002279111,0.0002679435,0.0004614235,0.0006238112,0.000351394,0.0003730491,0.0006218967,0.0008542719,0.001117408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004215689,"about_ca_system_score_gemma":0.0004389376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001920572,"about_ca_topic_score_gemma":0.003325418,"domain_scores_codex":[0.9984951,0.0003619585,0.000287091,0.0002343407,0.0005296207,0.00009196689],"domain_scores_gemma":[0.9982647,0.0005820286,0.00009757574,0.0004378631,0.0005373739,0.00008035605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003228705,0.0001569804,0.008987004,0.00017608,0.00004759584,0.0005262914,0.0003512799,0.0004466496,0.9748884,0.0002784252,0.0004503781,0.01336806],"study_design_scores_gemma":[0.00006620587,0.001607607,0.03755118,0.00005627942,0.0001782137,0.003621073,0.0003374666,0.00252424,0.9362679,0.0002626228,0.01747826,0.00004896239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9090526,0.004016169,0.07581597,0.0004057096,0.0001482122,0.001508612,0.005447894,0.0004166618,0.003188194],"genre_scores_gemma":[0.8670397,0.002925638,0.1010496,0.0003274205,0.00003400343,0.001695045,0.01955081,0.0001762512,0.007201593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001924528,"threshold_uncertainty_score":0.009916604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859597535765816,"score_gpt":0.264537254079509,"score_spread":0.2459412787218508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}