{"id":"W4288060552","doi":"10.3390/cells11152307","title":"Effective Treatment of Patients Experiencing Primary, Acute HIV Infection Decreases Exhausted/Activated CD4+ T Cells and CD8+ T Memory Stem Cells","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"International Society for Advancement of Cytometry","keywords":"Human immunodeficiency virus (HIV); Stem cell; CD8; Cytotoxic T cell; Medicine; Primary cell; Gerontology; Immunology; Biology; Immune system; Cell biology; Cell; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034622,0.0002840185,0.0004412883,0.0001930299,0.0004038296,0.00001454477,0.0001026899,0.0001113576,0.0006652492],"category_scores_gemma":[0.000003624261,0.0002417912,0.0001275096,0.0001955779,0.0001643823,0.00009988265,0.0001705175,0.0001657003,0.0001966949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005490698,"about_ca_system_score_gemma":0.00008397521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004184283,"about_ca_topic_score_gemma":0.000007969181,"domain_scores_codex":[0.9982008,0.0005025339,0.0002878234,0.0004615248,0.0001055449,0.0004417966],"domain_scores_gemma":[0.9990903,0.0002760895,0.0001759253,0.0002993064,0.00007675905,0.00008167476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007702363,0.001863142,0.005520123,0.00004201305,0.00067585,0.00003590842,0.002752659,0.00004901015,0.9645497,0.000001815249,0.00137304,0.02236651],"study_design_scores_gemma":[0.004496912,0.003023799,0.007098332,0.00001402473,0.000150049,0.00001133252,0.0005487468,0.00000272832,0.9755281,0.000002516772,0.008929518,0.000193918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996011,0.0008458025,0.0000161919,0.000007570805,0.0005032062,0.001386286,0.0005759909,0.00005780114,0.000596142],"genre_scores_gemma":[0.9953188,0.0003495112,0.00002399125,0.00002045916,0.00001443408,0.0004644312,0.000484519,0.00002741417,0.003296496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02217259,"threshold_uncertainty_score":0.9859961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008387091214369553,"score_gpt":0.2273831528260751,"score_spread":0.2189960616117055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}