{"id":"W4288060552","doi":"10.3390/cells11152307","title":"Effective Treatment of Patients Experiencing Primary, Acute HIV Infection Decreases Exhausted/Activated CD4+ T Cells and CD8+ T Memory Stem Cells","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"International Society for Advancement of Cytometry","keywords":"Human immunodeficiency virus (HIV); Stem cell; CD8; Cytotoxic T cell; Medicine; Primary cell; Gerontology; Immunology; Biology; Immune system; Cell biology; Cell; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002105345,0.0002649237,0.000461444,0.0003559613,0.0002101408,0.0004170493,0.0001256289,0.0002428774,0.001267273],"category_scores_gemma":[0.001036856,0.0001144611,0.0001597856,0.0002008555,0.0001584708,0.0002201964,0.0001527762,0.0003642732,0.0001874487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001454169,"about_ca_system_score_gemma":0.0001586618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003383368,"about_ca_topic_score_gemma":0.0005826037,"domain_scores_codex":[0.9998465,0.00004494616,0.00001485416,0.00002631897,0.00003244187,0.00003492325],"domain_scores_gemma":[0.9996271,0.00009702096,0.0001167481,0.00001720216,0.00003635862,0.0001055285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004642982,0.001164846,0.8121426,0.0003286241,0.0001707921,0.001209221,0.0005772964,0.0004469027,0.05670973,0.0001026319,0.00112585,0.1213785],"study_design_scores_gemma":[0.0001253145,0.003433101,0.9884779,0.00003497912,0.0000989787,0.001630331,0.0001874655,0.0004371237,0.00408788,0.0001125596,0.001365423,0.000008812104],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972919,0.001752605,0.000146598,0.00006120018,0.00001080994,0.00002471273,0.0001048199,0.00001665593,0.0005905814],"genre_scores_gemma":[0.9988058,0.0003978003,0.0002170359,0.00007168014,0.00003933107,0.00001937754,0.0001943815,0.000002401976,0.0002522508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267273,"threshold_uncertainty_score":0.0042395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008387091214369553,"score_gpt":0.2273831528260751,"score_spread":0.2189960616117055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}