{"id":"W4288077717","doi":"10.1021/acsomega.2c02286","title":"Synthesis, Catalytic GPx-like Activity, and SET Reactions of Conformationally Constrained 2,7-Dialkoxy-Substituted Naphthalene-1,8-<i>peri-</i>diselenides","year":2022,"lang":"en","type":"article","venue":"ACS Omega","topic":"Organoselenium and organotellurium chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Catalysis; Naphthalene; Thiol; Hydrogen peroxide; Triethylamine; Medicinal chemistry; Peroxidase; Antioxidant; Photochemistry; Organic chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005202994,0.0002720197,0.0003760028,0.0001516468,0.0005928088,0.00002302546,0.000326742,0.0002260709,0.001120765],"category_scores_gemma":[0.0001911711,0.0003030849,0.00009623841,0.0003636904,0.0005105328,0.0002504321,0.0002558399,0.0007504149,0.00003019777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001021241,"about_ca_system_score_gemma":0.0003501323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007119002,"about_ca_topic_score_gemma":0.00001188968,"domain_scores_codex":[0.9983072,0.0002197797,0.0004578251,0.0003351661,0.0002929969,0.0003870351],"domain_scores_gemma":[0.9981925,0.0009031866,0.0003015467,0.0002828028,0.0001057261,0.0002142732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003544955,0.0003270517,0.002299674,0.0002740289,0.000350203,0.00004482711,0.0007685355,0.0003152907,0.9890896,0.0004958109,0.002968613,0.002711865],"study_design_scores_gemma":[0.001283457,0.000069302,0.001229041,0.0000142683,0.0002873315,0.0005424653,0.0005226023,0.0003322665,0.9007691,0.0001576499,0.09439213,0.0004004542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924629,0.0004448482,0.0000363353,0.0009073116,0.0006022942,0.0002998929,0.001391031,0.0001151995,0.003740146],"genre_scores_gemma":[0.9981006,0.0002822471,0.00009451853,0.0004893818,0.0001101786,0.00006934358,0.0001872953,0.00003105997,0.0006353234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09142351,"threshold_uncertainty_score":0.9999421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05335052009580301,"score_gpt":0.3459116828802418,"score_spread":0.2925611627844388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}