{"id":"W4288096104","doi":"10.1128/spectrum.02085-22","title":"Baicalein Acts against Candida albicans by Targeting Eno1 and Inhibiting Glycolysis","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Flavonoids in Medical Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Baicalein; Candida albicans; Glycolysis; Pharmacology; Chemistry; Medicine; Microbiology; Biology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005258869,0.0002812028,0.0002872997,0.0001362191,0.0001376545,0.0001523677,0.0001342665,0.0002096641,0.001085716],"category_scores_gemma":[0.00006447565,0.00005175645,0.000147776,0.0001041511,0.0001507343,0.0001626315,0.0001121195,0.0004556077,0.0001331995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002406502,"about_ca_system_score_gemma":0.000173043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008011955,"about_ca_topic_score_gemma":0.001709537,"domain_scores_codex":[0.9999695,0.000003531448,0.000002007834,0.000007262706,0.00001017032,0.000007547858],"domain_scores_gemma":[0.9999825,0.000002381902,0.000004696126,9.72233e-7,0.000002434862,0.000007134126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001563192,0.00003770423,0.000249092,0.0002098345,0.00001018928,0.00007553509,0.000008700867,0.0001827143,0.9953154,0.0002328063,0.0004138617,0.003107831],"study_design_scores_gemma":[0.0001324826,0.0003989476,0.007501167,0.00002593523,0.00003187065,0.0003123573,0.00002724601,0.002012599,0.9743004,0.0002351664,0.01500837,0.00001345107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677213,0.018081,0.003891874,0.001099333,0.0002190416,0.0001358462,0.001107191,0.0002885788,0.007455816],"genre_scores_gemma":[0.9872104,0.005022766,0.003903039,0.0002684135,0.00002720527,0.0000501478,0.0006450823,0.00001826507,0.002854731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085716,"threshold_uncertainty_score":0.003632128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006399937724364715,"score_gpt":0.2499221011750273,"score_spread":0.2435221634506626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}