{"id":"W4288429241","doi":"10.3389/fimmu.2022.892114","title":"Susceptibility to Infections During Acute Liver Injury Depends on Transient Disruption of Liver Macrophage Niche","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Universidade Federal de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Kupffer cell; Liver injury; Macrophage; Immune system; Medicine; Infiltration (HVAC); Monocyte; Immunology; Phagocytosis; Biology; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001920148,0.0002805754,0.0003452438,0.0002246711,0.0001634075,0.0003213036,0.00009915887,0.0002955722,0.0009760132],"category_scores_gemma":[0.0001685989,0.0001364757,0.0002839675,0.0001003483,0.0002525106,0.0002659994,0.0003457863,0.0008071958,0.0002971471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001877953,"about_ca_system_score_gemma":0.0001845305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002081723,"about_ca_topic_score_gemma":0.0002948553,"domain_scores_codex":[0.9997144,0.00005093837,0.00002735312,0.00004659534,0.00005098547,0.0001095904],"domain_scores_gemma":[0.9998311,0.00001255775,0.00005665046,0.00001707186,0.0000195265,0.00006313153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005576962,0.00008744976,0.002010646,0.0000771983,0.000007905865,0.0001815691,0.0000590286,0.00003828074,0.9943439,0.00009572857,0.00006756654,0.002473106],"study_design_scores_gemma":[0.00006484277,0.003550042,0.1033147,0.00006312155,0.00006802188,0.002325322,0.0004159042,0.001270486,0.8832033,0.0003279359,0.005371893,0.00002438271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943945,0.002587408,0.001710236,0.00009220654,0.00002950732,0.00003728133,0.0001444103,0.00005893199,0.0009453176],"genre_scores_gemma":[0.9975117,0.0007006367,0.0006492242,0.00006185485,0.00001334448,0.00005957459,0.0001766809,0.000007920252,0.0008191193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009760132,"threshold_uncertainty_score":0.003265142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006474788320171866,"score_gpt":0.2319895585222253,"score_spread":0.2255147702020535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}