{"id":"W4288435843","doi":"10.3390/cancers14153672","title":"CD109 Is a Critical Determinant of EGFR Expression and Signaling, and Tumorigenicity in Squamous Cell Carcinoma Cells","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Cancer research; Protein kinase B; Biology; Metastasis; Signal transduction; Cancer; Cell; Pathology; Medicine; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001412887,0.0001050643,0.0002795493,0.0000836754,0.00006600415,0.000005452847,0.00004556765,0.00002953878,0.0002722506],"category_scores_gemma":[0.00001577194,0.0000990574,0.00004551055,0.0001147818,0.0001122293,0.00002837591,0.00009168246,0.0001732432,3.813164e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003658091,"about_ca_system_score_gemma":0.0002928126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001616922,"about_ca_topic_score_gemma":0.00004527316,"domain_scores_codex":[0.999093,0.00004194287,0.0002053968,0.0002668857,0.0001879749,0.0002047823],"domain_scores_gemma":[0.999566,0.00007064454,0.00005283114,0.0001477775,0.00002618954,0.0001366142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006490295,0.0002032128,0.01631655,0.001004202,0.000005610826,0.0002913061,0.00407155,0.00004336244,0.9711091,0.00001758708,0.001790405,0.004498116],"study_design_scores_gemma":[0.004192908,0.0006412232,0.002225509,0.00005947322,0.00009094062,0.00004408059,0.002327578,0.0004538861,0.9835568,0.00003093998,0.006218939,0.0001576931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940097,0.005013974,0.00002200812,0.00008975559,0.0001436939,0.0001960448,0.00006595397,0.000005962926,0.0004529553],"genre_scores_gemma":[0.9989247,0.0001223415,0.0003438046,0.0003357972,0.00004059041,0.00003593421,0.000002226904,0.0000141619,0.0001803919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01409104,"threshold_uncertainty_score":0.4039444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600355935745839,"score_gpt":0.2712174589435869,"score_spread":0.2552138995861285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}