{"id":"W4288435843","doi":"10.3390/cancers14153672","title":"CD109 Is a Critical Determinant of EGFR Expression and Signaling, and Tumorigenicity in Squamous Cell Carcinoma Cells","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Cancer research; Protein kinase B; Biology; Metastasis; Signal transduction; Cancer; Cell; Pathology; Medicine; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008313455,0.0001865747,0.0001680173,0.0002138843,0.0001956038,0.0003059437,0.0001540315,0.000232634,0.001766841],"category_scores_gemma":[0.0001732809,0.00009220493,0.0001493034,0.0001932928,0.0001451703,0.0001602797,0.0002091705,0.0003220592,0.0004830108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281109,"about_ca_system_score_gemma":0.0002054715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006371979,"about_ca_topic_score_gemma":0.0007874052,"domain_scores_codex":[0.9998698,0.00001436273,0.00001448099,0.00002604046,0.00005625796,0.00001907169],"domain_scores_gemma":[0.9998789,0.00001812733,0.00003320168,0.00001158433,0.00001939561,0.00003875474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004808731,0.00001807548,0.001010963,0.0000190981,0.00000294042,0.0001111826,0.000006006424,0.00001770867,0.9978636,0.00005527906,0.0000522741,0.0007947759],"study_design_scores_gemma":[0.000009679097,0.0001553986,0.02995247,0.000005898251,0.00001706034,0.001005441,0.00005421712,0.0005749093,0.9647421,0.00004884525,0.003429914,0.000004134855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939539,0.001498378,0.001541759,0.0001098533,0.00002052028,0.00003337813,0.0005256408,0.00005719729,0.002259447],"genre_scores_gemma":[0.9966893,0.0004429055,0.0007743431,0.00003018169,0.0000048005,0.00002129422,0.0005862332,0.000008208957,0.001442826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001766841,"threshold_uncertainty_score":0.005910635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600355935745839,"score_gpt":0.2712174589435869,"score_spread":0.2552138995861285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}