{"id":"W4288473064","doi":"10.1266/ggs.22-00012","title":"Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast <i>Schizosaccharomyces pombe</i>","year":2022,"lang":"en","type":"article","venue":"Genes & Genetic Systems","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Otsuka Toshimi Scholarship Foundation; Japan Society for the Promotion of Science; Cancer Research Society","keywords":"Schizosaccharomyces pombe; Mating of yeast; Biology; Heterochromatin; Schizosaccharomyces; Heterochromatin protein 1; Euchromatin; Genetics; Histone; Histone H2A; Histone methylation; Mutant; Cell biology; Chromatin; DNA methylation; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004044247,0.0003299827,0.0003405197,0.0001812768,0.0003951037,0.0001464525,0.0002852607,0.000157658,0.00005774782],"category_scores_gemma":[0.0001126458,0.0003160235,0.00004413645,0.0003983244,0.00005348232,0.00000962009,0.0006507012,0.0001348391,0.000007212091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004841751,"about_ca_system_score_gemma":0.0001067248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005217075,"about_ca_topic_score_gemma":0.00006715111,"domain_scores_codex":[0.9974622,0.0004669336,0.0004740616,0.0006842459,0.0004560686,0.0004564496],"domain_scores_gemma":[0.9991058,0.00004642896,0.000183714,0.0003835955,0.00009773543,0.0001827323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003427472,0.0000461602,0.05064638,0.0002090004,0.00003713905,0.000009913464,0.0005392428,0.001421499,0.9445877,0.000009104489,0.0002238008,0.002235787],"study_design_scores_gemma":[0.003593157,0.00291072,0.4885075,0.0004122664,0.000106647,0.001203203,0.002993378,0.02034955,0.4630948,0.00005376665,0.01463682,0.002138172],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845093,0.01401168,0.0002052545,0.00003291063,0.0004401987,0.0006277684,0.00005044446,0.00003102496,0.00009142447],"genre_scores_gemma":[0.9980711,0.0006242662,0.0004534072,0.00002312559,0.0002052382,0.00006013702,0.0002190884,0.00007411946,0.0002694988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4814929,"threshold_uncertainty_score":0.9999292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00992949667141432,"score_gpt":0.2362759592856432,"score_spread":0.2263464626142289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}