{"id":"W4288749431","doi":"10.1186/s13550-022-00915-w","title":"Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases","year":2022,"lang":"en","type":"article","venue":"EJNMMI Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atuka (Canada); University Health Network; McGill University; Montreal Neurological Institute and Hospital; University of Alberta","funders":"University of Alberta; Weston Brain Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Medicine; In vivo; Kinase; Peripheral; Tropomyosin; Receptor; Internal medicine; Cell biology; Actin; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000460343,0.0006047192,0.0004290981,0.0001583485,0.0002351999,0.0003621886,0.0005593821,0.0004748312,0.002202144],"category_scores_gemma":[0.0003715262,0.0003161586,0.0002948593,0.0001793779,0.0002126577,0.000247136,0.0002011552,0.0005579194,0.0008491797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003984586,"about_ca_system_score_gemma":0.0003358286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001970573,"about_ca_topic_score_gemma":0.001803423,"domain_scores_codex":[0.9997537,0.0000637828,0.00001107335,0.00008345131,0.00004224382,0.00004584185],"domain_scores_gemma":[0.9997544,0.00008338693,0.00005115091,0.00003576079,0.00004682894,0.00002851572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001554913,0.00003002902,0.0001202631,0.0000590857,0.000005564572,0.00005222157,0.00001760011,0.0001829167,0.9981584,0.0001287784,0.00009700849,0.0009925372],"study_design_scores_gemma":[0.00002127036,0.0003596659,0.0007056615,0.000007487149,0.00001218508,0.0002990572,0.00001409115,0.00167815,0.9944158,0.00002165768,0.002459478,0.000005567735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9102903,0.004602601,0.07525491,0.0002281631,0.00008372281,0.0002388804,0.001315832,0.0003595865,0.007625976],"genre_scores_gemma":[0.945995,0.002415695,0.04180375,0.0001154825,0.00003672684,0.0002130326,0.001462672,0.0001099206,0.007847608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002202144,"threshold_uncertainty_score":0.007366955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1474191507350246,"score_gpt":0.4392329236631014,"score_spread":0.2918137729280769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}