{"id":"W4288855507","doi":"10.1210/endrev/bnac018","title":"Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease","year":2022,"lang":"en","type":"article","venue":"Endocrine Reviews","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Type 2 diabetes; Steatohepatitis; Steatosis; Fatty liver; Glucagon-like peptide-1; Inflammation; Nonalcoholic fatty liver disease; Liver disease; Endocrinology; Internal medicine; Diabetes mellitus; Bioinformatics; Biology; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004735639,0.0004952783,0.0004351435,0.000561437,0.0002235674,0.0006586598,0.0004095815,0.0009717011,0.006947167],"category_scores_gemma":[0.0002836077,0.0001034374,0.0004890651,0.0001980939,0.0002943282,0.0007271438,0.0006182265,0.001820395,0.002324704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003693425,"about_ca_system_score_gemma":0.0005196973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001992732,"about_ca_topic_score_gemma":0.0006777508,"domain_scores_codex":[0.9998237,0.0000430783,0.00001360012,0.00002029594,0.00007288947,0.00002637365],"domain_scores_gemma":[0.9999079,0.0000161166,0.00002082505,0.000004419033,0.00002422441,0.00002652262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006171083,0.0004498171,0.0003268299,0.003529507,0.00008915251,0.0007077572,0.000114064,0.0004172644,0.05576324,0.02253988,0.0845777,0.8308677],"study_design_scores_gemma":[0.0003827173,0.001237942,0.001356195,0.001179091,0.0001135656,0.00155117,0.000075435,0.0006070258,0.008090952,0.009534791,0.9758348,0.00003636024],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006621521,0.9413018,0.005019217,0.01864002,0.006332898,0.0001203787,0.0002160478,0.0002777272,0.02147039],"genre_scores_gemma":[0.04606952,0.9073357,0.006798955,0.009856965,0.00606465,0.0001681634,0.000300024,0.0000445877,0.02336139],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006947167,"threshold_uncertainty_score":0.02324057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06442228544527856,"score_gpt":0.3287426774309487,"score_spread":0.2643203919856701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}