{"id":"W4288858747","doi":"10.1016/b978-0-12-821618-7.00186-3","title":"Internal Ribosome Entry Sites: Form and Function","year":2022,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Internal ribosome entry site; Ribosome; Translation (biology); Messenger RNA; Cell biology; Protein biosynthesis; Eukaryotic translation; Biology; Ribosomal binding site; Initiation factor; Eukaryotic initiation factor; EIF4E; Eukaryotic Ribosome; Mechanism (biology); RNA; Gene; Genetics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002775754,0.001218877,0.0009203816,0.0006858625,0.0005018213,0.002525717,0.000944683,0.001414935,0.02565877],"category_scores_gemma":[0.0002310255,0.0005991706,0.0003778515,0.0012789,0.0008333999,0.001781898,0.0007068514,0.002578376,0.02743482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007442864,"about_ca_system_score_gemma":0.0004616191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005215731,"about_ca_topic_score_gemma":0.0005720167,"domain_scores_codex":[0.999889,0.00001284687,0.000006743848,0.00002981024,0.00004795228,0.00001357276],"domain_scores_gemma":[0.9999319,0.0000271976,0.000007367702,0.00001111577,0.00001137606,0.00001097694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002068813,0.0001039931,0.0001211206,0.0009777424,0.00001610864,0.0003443886,0.000337704,0.001002118,0.1505015,0.1743254,0.1235558,0.5485073],"study_design_scores_gemma":[0.00001477817,0.00006485054,0.0003897996,0.0001450581,0.000009847771,0.000639432,0.00009663125,0.0003715578,0.017837,0.03046641,0.9499425,0.00002211543],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01206089,0.381184,0.04102053,0.00477215,0.007603603,0.00009348401,0.001598512,0.001608599,0.5500581],"genre_scores_gemma":[0.02494881,0.1017447,0.01695077,0.001451381,0.001400683,0.0001363613,0.002205782,0.000459955,0.8507015],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.02565877,"threshold_uncertainty_score":0.08583707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02385006813869277,"score_gpt":0.2786418371995675,"score_spread":0.2547917690608747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}