{"id":"W4288969690","doi":"10.1016/j.jbc.2022.102330","title":"Meeting report: Flux-independent signaling by ionotropic receptors: Unforeseen roles, complexities, and challenges","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"American Society for Biochemistry and Molecular Biology","keywords":"Ionotropic effect; Receptor; Flux (metallurgy); Cell biology; Signal transduction; Chemistry; Computational biology; Biology; Biochemistry; Glutamate receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004697151,0.001776012,0.001028938,0.001264436,0.001726449,0.007120276,0.001859188,0.009841591,0.1327175],"category_scores_gemma":[0.005390243,0.0004492281,0.001110666,0.0009407193,0.0008471298,0.003547351,0.002979957,0.004958637,0.1132454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001610541,"about_ca_system_score_gemma":0.003534902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001258013,"about_ca_topic_score_gemma":0.001645547,"domain_scores_codex":[0.9981124,0.0002185256,0.0001630736,0.0003220944,0.0008309765,0.00035283],"domain_scores_gemma":[0.9935338,0.0006928327,0.0003632671,0.0001875654,0.003392393,0.001830125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001371751,0.00004361659,0.0001891187,0.0003825118,0.000009870751,0.0001919096,0.00003385538,0.00003521051,0.0005698326,0.000522646,0.9721147,0.0257696],"study_design_scores_gemma":[0.00002480632,0.00007553355,0.0006489043,0.0003070092,0.0000112331,0.0001635535,0.0001107326,0.0000594337,0.0003207164,0.0006913053,0.9975701,0.00001661314],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.003331584,0.05168604,0.001803075,0.2940539,0.5198135,0.0008522444,0.007199998,0.0006797789,0.1205799],"genre_scores_gemma":[0.0198282,0.06172035,0.001957506,0.08296599,0.4211918,0.0008827749,0.005799733,0.0005862372,0.4050675],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.1327175,"threshold_uncertainty_score":0.4439844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1132677268971406,"score_gpt":0.3201793846515651,"score_spread":0.2069116577544245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}