{"id":"W4289111514","doi":"10.3390/cancers14153698","title":"Immunology Meets Bioengineering: Improving the Effectiveness of Glioblastoma Immunotherapy","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; CancerCare Manitoba","funders":"","keywords":"Immunotherapy; Oncolytic virus; Medicine; Glioblastoma; Radiation therapy; Cancer immunotherapy; Cancer; Cancer research; Immune system; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004793948,0.0005387874,0.001405769,0.0002536803,0.00009072777,0.0000201011,0.0008684985,0.000241245,0.0001689401],"category_scores_gemma":[0.00003552902,0.0004138405,0.0005260504,0.0006937244,0.0001283528,0.00007537074,0.0001012381,0.0007118089,0.000008903914],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003883699,"about_ca_system_score_gemma":0.0005660279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008145248,"about_ca_topic_score_gemma":0.000006051085,"domain_scores_codex":[0.9983816,0.0001248878,0.0005501363,0.0002834237,0.0002170865,0.000442896],"domain_scores_gemma":[0.9981572,0.0008115614,0.0001964521,0.0007701909,0.00002449589,0.00004009468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006198214,0.000003682498,1.530843e-7,0.02196893,0.001380892,0.000008899849,0.0000824252,0.01222035,0.002257236,0.0002007555,0.00005082807,0.9617639],"study_design_scores_gemma":[0.0003084478,0.000146321,6.836438e-7,0.002379835,0.0002564737,0.00003249531,0.00002130028,0.0003558622,0.001010308,0.0000209302,0.9950395,0.0004279007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008563967,0.9944601,0.0006180264,5.814483e-7,0.003233292,0.0009448708,0.000116942,0.000248981,0.0002915465],"genre_scores_gemma":[0.0006736919,0.9982092,0.00003923173,0.000004201149,0.0001045964,0.0006745926,0.00002832324,0.0002501009,0.00001602327],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9949886,"threshold_uncertainty_score":0.9999402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406714812827987,"score_gpt":0.2459099856837001,"score_spread":0.2318428375554202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}