{"id":"W4289261182","doi":"10.1101/2022.07.31.22277301","title":"The Blood Proteome of Imminent Lung Cancer Diagnosis","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto","funders":"National Cancer Institute; Cancer Research UK; Institut National Du Cancer; Fondation ARC pour la Recherche sur le Cancer; Centre International de Recherche sur le Cancer; World Health Organization","keywords":"Lung cancer; Cancer; Medicine; Internal medicine; Metastasis; Oncology; Biomarker; Odds ratio; Lung; Chemokine; Pathology; Immunology; Inflammation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006282129,0.0002709626,0.0003930327,0.0008371322,0.000258338,0.0009998636,0.0001860109,0.0004628222,0.0009730885],"category_scores_gemma":[0.001261941,0.0002207926,0.0002637538,0.001066126,0.0002162775,0.0002654337,0.0003852303,0.0004418787,0.0003939444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003201383,"about_ca_system_score_gemma":0.0002420089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001838369,"about_ca_topic_score_gemma":0.001384325,"domain_scores_codex":[0.9996641,0.00009506048,0.00002533608,0.0000805173,0.00009204831,0.00004303455],"domain_scores_gemma":[0.9993117,0.0001344945,0.0003184865,0.00005113972,0.000114269,0.00006999035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001068651,0.00005452641,0.8969266,0.0001914652,0.00024406,0.0005647678,0.0001995646,0.0003125948,0.08849659,0.0001923951,0.0008467535,0.01090202],"study_design_scores_gemma":[0.00001005228,0.0001005499,0.9886445,0.00001900577,0.00006110729,0.0007017929,0.0001102378,0.001187668,0.007504891,0.0002028063,0.001450487,0.00000709393],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939176,0.003423465,0.0006447932,0.0001668526,0.00002787833,0.000007240677,0.001272882,0.00002144636,0.0005179092],"genre_scores_gemma":[0.9973415,0.0005917544,0.0005451401,0.00009356483,0.00002351274,0.00000529713,0.0009794963,0.000004150032,0.0004155831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838369,"threshold_uncertainty_score":0.003655374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904364612096589,"score_gpt":0.3775979276224786,"score_spread":0.3485542815015127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}