{"id":"W4289261182","doi":"10.1101/2022.07.31.22277301","title":"The Blood Proteome of Imminent Lung Cancer Diagnosis","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto","funders":"National Cancer Institute; Cancer Research UK; Institut National Du Cancer; Fondation ARC pour la Recherche sur le Cancer; Centre International de Recherche sur le Cancer; World Health Organization","keywords":"Lung cancer; Cancer; Medicine; Internal medicine; Metastasis; Oncology; Biomarker; Odds ratio; Lung; Chemokine; Pathology; Immunology; Inflammation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000774607,0.0002528118,0.0005796475,0.0001149567,0.0002251725,0.00002145104,0.0005222406,0.00008670995,0.001097105],"category_scores_gemma":[0.0006377854,0.000159237,0.0002621139,0.0002402578,0.0002442984,0.00001618781,0.002112917,0.001088054,0.000003165501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003519016,"about_ca_system_score_gemma":0.0006592221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001348291,"about_ca_topic_score_gemma":0.0001590797,"domain_scores_codex":[0.9974242,0.0001445934,0.0004299172,0.0004701697,0.001111098,0.0004199624],"domain_scores_gemma":[0.9980965,0.0003078492,0.0002559153,0.0009791693,0.0002434836,0.0001171251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001822233,0.0002541674,0.9766753,0.003033085,0.002197733,0.00009663977,0.0008511213,0.0000535097,0.0008712139,0.0000737354,0.01415865,0.001552667],"study_design_scores_gemma":[0.002855248,0.0006471809,0.752846,0.002455306,0.002543417,0.00001379479,0.0004123854,0.000222036,0.03532374,0.000297473,0.2017758,0.0006076001],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9262576,0.05130959,0.000004583495,0.01651384,0.0009278488,0.003159966,0.0002066114,0.00006115378,0.001558876],"genre_scores_gemma":[0.9061293,0.05003129,0.0001086119,0.0001502641,0.0006461329,0.03594556,0.00003012997,0.00007845298,0.006880241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2238293,"threshold_uncertainty_score":0.999816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904364612096589,"score_gpt":0.3775979276224786,"score_spread":0.3485542815015127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}