{"id":"W4289262055","doi":"10.1371/journal.pone.0269619","title":"The bending rigidity of the red blood cell cytoplasmic membrane","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Tech University; Canadian Blood Services; McMaster University","funders":"National Heart, Lung, and Blood Institute; National Science Foundation of Sri Lanka; Natural Sciences and Engineering Research Council of Canada; Division of Materials Research; McMaster University; National Institute of Standards and Technology; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Government of Ontario; National Institute of General Medical Sciences; Canadian Blood Services; Ministero dello Sviluppo Economico; U.S. Department of Commerce; National Institutes of Health; National Science Foundation","keywords":"Spectrin; Membrane; Cytoplasm; Biophysics; Red blood cell; Lipid bilayer; Chemistry; Flexural rigidity; Cell membrane; Adenosine triphosphate; Biology; Biochemistry; Cell; Physics; Cytoskeleton; Thermodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001583553,0.0002092285,0.0001551438,0.000231452,0.0001973901,0.0003338722,0.0002628118,0.0002691551,0.001723908],"category_scores_gemma":[0.0004854384,0.0001869625,0.000119762,0.0001559514,0.0004323975,0.0003595635,0.000309264,0.0003658257,0.0002751167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001741096,"about_ca_system_score_gemma":0.0001666066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004340833,"about_ca_topic_score_gemma":0.0003417004,"domain_scores_codex":[0.9998986,0.00001233354,0.000005560792,0.00003031025,0.00003358227,0.00001960745],"domain_scores_gemma":[0.9998494,0.00006398333,0.00003732253,0.00001747345,0.00001632262,0.00001542267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007506406,0.00002196729,0.003527951,0.0001188302,0.00002597095,0.0002642545,0.0001150661,0.01411666,0.9715802,0.004271722,0.0001453711,0.005736982],"study_design_scores_gemma":[0.00003083273,0.0003972868,0.07228197,0.00009756697,0.00005761136,0.001515109,0.0003651889,0.2263535,0.6843693,0.009106806,0.005256119,0.0001685719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983193,0.001198245,0.01140521,0.0001740352,0.00002635604,0.00001165834,0.0002464013,0.00007416929,0.003670745],"genre_scores_gemma":[0.997631,0.0003610713,0.001486989,0.00001661713,0.000003466715,0.000008823305,0.00009823588,0.000006806427,0.0003871251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001723908,"threshold_uncertainty_score":0.005767047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03557352991115747,"score_gpt":0.2146296813018805,"score_spread":0.1790561513907231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}