{"id":"W4289262055","doi":"10.1371/journal.pone.0269619","title":"The bending rigidity of the red blood cell cytoplasmic membrane","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Tech University; Canadian Blood Services; McMaster University","funders":"National Heart, Lung, and Blood Institute; National Science Foundation of Sri Lanka; Natural Sciences and Engineering Research Council of Canada; Division of Materials Research; McMaster University; National Institute of Standards and Technology; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Government of Ontario; National Institute of General Medical Sciences; Canadian Blood Services; Ministero dello Sviluppo Economico; U.S. Department of Commerce; National Institutes of Health; National Science Foundation","keywords":"Spectrin; Membrane; Cytoplasm; Biophysics; Red blood cell; Lipid bilayer; Chemistry; Flexural rigidity; Cell membrane; Adenosine triphosphate; Biology; Biochemistry; Cell; Physics; Cytoskeleton; Thermodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001815207,0.00006611038,0.0001761792,0.00002492332,0.0003552625,0.000002913411,0.0001328719,0.00002302735,0.0005343839],"category_scores_gemma":[0.00007927176,0.0000394062,0.00007897212,0.0001724116,0.00006807844,0.00001222049,0.0001225828,0.0003013716,0.00001421195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002647334,"about_ca_system_score_gemma":0.00005410764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001201695,"about_ca_topic_score_gemma":0.000006654821,"domain_scores_codex":[0.9991633,0.0001277745,0.0001603061,0.000126905,0.0002853236,0.0001363694],"domain_scores_gemma":[0.9993053,0.0001604748,0.000101738,0.0003638857,0.00003801273,0.00003055352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000195913,0.0009627661,0.003035289,0.00008790189,0.0001269685,0.000004417954,0.0001516113,0.00001352368,0.9943298,0.0001384538,0.0009132478,0.00004006839],"study_design_scores_gemma":[0.001804924,0.0005319843,0.006761279,0.00004616228,0.0005279552,0.00002647911,0.0003165659,0.000363199,0.9833056,0.0001891745,0.006040947,0.00008573609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908929,0.000182205,0.000001137021,0.001746223,0.0002662743,0.0002443001,0.00001228695,0.00002837088,0.006626236],"genre_scores_gemma":[0.9921186,0.0001228422,0.00008047351,0.0004219683,0.0001146954,0.00002978302,0.000009798109,0.0000110191,0.007090801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01102425,"threshold_uncertainty_score":0.5851129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03557352991115747,"score_gpt":0.2146296813018805,"score_spread":0.1790561513907231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}