{"id":"W4289524405","doi":"10.1111/all.15464","title":"Fel d 1 surface expression on plant‐made <i>e</i>Bioparticles combines potent immune activation and hypoallergenicity","year":2022,"lang":"en","type":"letter","venue":"Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universitaire Ziekenhuizen Leuven, KU Leuven; Fonds Wetenschappelijk Onderzoek","keywords":"CD80; Immunogenicity; Immune system; Adjuvant; CD86; Alum; Immunology; Allergen; Immunoglobulin E; Allergy; Chemistry; Antibody; Medicine; In vitro; T cell; CD40; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006297349,0.0003895391,0.0002840672,0.000111923,0.0002622718,0.0006188697,0.0005336931,0.0009814416,0.0042945],"category_scores_gemma":[0.0009581863,0.000158294,0.000223172,0.0001001597,0.0003576308,0.0003962077,0.0002383082,0.001354028,0.001606014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004720038,"about_ca_system_score_gemma":0.0001288623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001785879,"about_ca_topic_score_gemma":0.0002548482,"domain_scores_codex":[0.9997092,0.00006472667,0.00003454559,0.00006760932,0.0000876396,0.00003629037],"domain_scores_gemma":[0.9994399,0.0002433274,0.00004906948,0.00002558981,0.0001755032,0.00006659901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002870062,0.0002646858,0.002292622,0.002141341,0.0001034145,0.005471192,0.0002081558,0.0004560921,0.7670967,0.002071707,0.1447316,0.07229241],"study_design_scores_gemma":[0.00009591644,0.0006712814,0.003093682,0.00009608993,0.0001496134,0.003475461,0.0001411328,0.002530434,0.4551762,0.000526315,0.5340077,0.00003617755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.473284,0.1306468,0.03990834,0.1295987,0.2059486,0.0003137214,0.001508712,0.0009560045,0.01783514],"genre_scores_gemma":[0.809342,0.03350572,0.008447389,0.02896171,0.03934459,0.0001465912,0.001184227,0.0002830508,0.07878472],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0042945,"threshold_uncertainty_score":0.01436651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02212755136352233,"score_gpt":0.2271896336351123,"score_spread":0.20506208227159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}