{"id":"W4289524405","doi":"10.1111/all.15464","title":"Fel d 1 surface expression on plant‐made <i>e</i>Bioparticles combines potent immune activation and hypoallergenicity","year":2022,"lang":"en","type":"letter","venue":"Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universitaire Ziekenhuizen Leuven, KU Leuven; Fonds Wetenschappelijk Onderzoek","keywords":"CD80; Immunogenicity; Immune system; Adjuvant; CD86; Alum; Immunology; Allergen; Immunoglobulin E; Allergy; Chemistry; Antibody; Medicine; In vitro; T cell; CD40; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001391251,0.0004042586,0.0005863513,0.0001120239,0.0003053277,0.00004338199,0.0001239582,0.0004684488,0.0005938704],"category_scores_gemma":[0.00006279018,0.0003575208,0.0001404515,0.000128773,0.00006981751,0.00009082285,0.0001542776,0.001136357,0.00001874971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001165238,"about_ca_system_score_gemma":0.00006674253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001991848,"about_ca_topic_score_gemma":0.00000603228,"domain_scores_codex":[0.9976461,0.0001851063,0.0004844054,0.0005953124,0.0007065544,0.0003825283],"domain_scores_gemma":[0.998876,0.000185787,0.0002888906,0.0004650658,0.00008607144,0.00009816141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007110845,0.0002034225,0.00007067596,0.0001128626,0.0002732004,0.0005049935,0.0003377381,0.0003864003,0.06914543,0.0000976462,0.9276342,0.0005223579],"study_design_scores_gemma":[0.002785231,0.0009277406,0.007751791,0.0005024882,0.00007924491,0.0002636456,0.0001740046,0.001335535,0.02716637,0.0002201293,0.9580883,0.0007054636],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5803121,0.0009658114,0.0000810931,0.4140205,0.0008216441,0.0007539112,0.0001135066,0.0002185655,0.002712838],"genre_scores_gemma":[0.6198441,0.003559549,0.0003514047,0.358262,0.001759288,0.00005612354,0.008465807,0.0001995227,0.007502228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05575855,"threshold_uncertainty_score":0.9998877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02212755136352233,"score_gpt":0.2271896336351123,"score_spread":0.20506208227159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}