{"id":"W4289524747","doi":"10.3389/fimmu.2022.956156","title":"Shifting gears: Id3 enables recruitment of E proteins to new targets during T cell development and differentiation","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cellular differentiation; Biology; Cell biology; Computational biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002994516,0.0002858497,0.0002720055,0.0002530488,0.0004528683,0.0008660636,0.0004885105,0.0005659566,0.002931305],"category_scores_gemma":[0.0003925992,0.0002844851,0.0004052609,0.0001890462,0.0006679835,0.0008686963,0.00109777,0.001067014,0.001225871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009399734,"about_ca_system_score_gemma":0.0004195065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001038115,"about_ca_topic_score_gemma":0.001275689,"domain_scores_codex":[0.999729,0.00002515175,0.00001719172,0.00007031891,0.00007513774,0.0000833387],"domain_scores_gemma":[0.9998043,0.00003360198,0.00003596128,0.00004565992,0.00002147362,0.00005902266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002127857,0.00003708585,0.001430805,0.00007584635,0.000008476572,0.0002089666,0.00009366953,0.00103717,0.9848413,0.00409626,0.0003909353,0.007566744],"study_design_scores_gemma":[0.00002421935,0.0001359189,0.003818832,0.00001545866,0.00001676233,0.0005353933,0.0001092507,0.007567377,0.9716191,0.001932215,0.01419582,0.00002962787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9193757,0.003299305,0.06371669,0.0006347727,0.0002297657,0.00005872881,0.0005144975,0.0009945148,0.01117607],"genre_scores_gemma":[0.9848727,0.0005601125,0.008823509,0.0002393584,0.00001768162,0.00002791829,0.0002215464,0.00009410024,0.005142981],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002931305,"threshold_uncertainty_score":0.009806156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03258369454458649,"score_gpt":0.2558143320921381,"score_spread":0.2232306375475516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}