{"id":"W4289550065","doi":"10.1128/msystems.00264-22","title":"The Sixth Element: a 102-kb RepABC Plasmid of Xenologous Origin Modulates Chromosomal Gene Expression in Dinoroseobacter shibae","year":2022,"lang":"en","type":"article","venue":"mSystems","topic":"Microbial Community Ecology and Physiology","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Deutsche Forschungsgemeinschaft","keywords":"Plasmid; Extrachromosomal DNA; Replicon; Biology; Genetics; Gene; Regulon; Genome; Population; Molecular biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009885337,0.000250846,0.0002049911,0.0001774111,0.00009514325,0.0002210529,0.0001434045,0.0002548902,0.001176755],"category_scores_gemma":[0.0001872951,0.0001003583,0.0001276571,0.0001098162,0.0002165178,0.0001351801,0.0002745698,0.0004014279,0.0002199632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002431751,"about_ca_system_score_gemma":0.0001181768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008072743,"about_ca_topic_score_gemma":0.0007321701,"domain_scores_codex":[0.9998604,0.00002894592,0.00001032441,0.00002984489,0.00003106685,0.00003927034],"domain_scores_gemma":[0.9998667,0.00003621705,0.00002004315,0.0000149679,0.00001200915,0.00005003881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007778481,0.000017493,0.0002237863,0.00001161304,7.449707e-7,0.00001980179,0.00001296629,0.00001480126,0.9992933,0.00002473627,0.000005185458,0.000297731],"study_design_scores_gemma":[0.00001858494,0.0006876417,0.02206428,0.000006544328,0.000009127604,0.0001840165,0.0001684301,0.0009922918,0.9750134,0.00006343485,0.0007842181,0.000007959674],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999206,0.0001119173,0.0003495106,0.00003709366,0.000007262382,0.000003292228,0.00005701138,0.00001340969,0.0002145098],"genre_scores_gemma":[0.9985042,0.00006021241,0.00038424,0.00001802977,0.000002559785,0.000005068631,0.0001546543,0.000006414185,0.0008646859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001176755,"threshold_uncertainty_score":0.003936589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010293357136653,"score_gpt":0.214664632650357,"score_spread":0.204371275513704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}