{"id":"W4289550065","doi":"10.1128/msystems.00264-22","title":"The Sixth Element: a 102-kb RepABC Plasmid of Xenologous Origin Modulates Chromosomal Gene Expression in Dinoroseobacter shibae","year":2022,"lang":"en","type":"article","venue":"mSystems","topic":"Microbial Community Ecology and Physiology","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Deutsche Forschungsgemeinschaft","keywords":"Plasmid; Extrachromosomal DNA; Replicon; Biology; Genetics; Gene; Regulon; Genome; Population; Molecular biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005453416,0.000120573,0.0002121241,0.000030739,0.0005035781,0.000009548669,0.00056617,0.0000710206,0.002678185],"category_scores_gemma":[0.00001940183,0.00009209308,0.00005135023,0.000173937,0.00017252,0.00005580746,0.0008213529,0.0003123418,0.00007608256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191731,"about_ca_system_score_gemma":0.00001406398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009127734,"about_ca_topic_score_gemma":0.001581936,"domain_scores_codex":[0.9983081,0.0006665353,0.000345808,0.0002300601,0.0001394655,0.0003100263],"domain_scores_gemma":[0.9991628,0.0001751032,0.0001636837,0.0004614003,0.000004115024,0.00003288499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000139323,0.0001798402,0.08462034,0.00001426978,0.00001510047,0.0000128704,0.00146372,0.004863351,0.905215,0.00009761628,0.003154777,0.0002238137],"study_design_scores_gemma":[0.003175194,0.001889411,0.2674824,0.00007932138,0.00003318179,0.0001751871,0.002140212,0.003805284,0.2744879,0.002392959,0.4433617,0.0009771817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977016,0.0001356916,0.000006415733,0.00008582855,0.0003190147,0.0003004119,0.00003256115,0.00002005413,0.001398443],"genre_scores_gemma":[0.9991937,0.00001961683,0.00004453095,0.00007108364,0.00002707449,0.00009405467,0.00004109607,0.00001019691,0.0004986088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.630727,"threshold_uncertainty_score":0.9982335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010293357136653,"score_gpt":0.214664632650357,"score_spread":0.204371275513704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}