{"id":"W4289594701","doi":"10.1111/jdv.18474","title":"Super‐response to guselkumab treatment in patients with moderate‐to‐severe psoriasis: age, body weight, baseline Psoriasis Area and Severity Index, and baseline Investigator's Global Assessment scores predict complete skin clearance","year":2022,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Janssen Research and Development","keywords":"Medicine; Psoriasis Area and Severity Index; Psoriasis; Internal medicine; Logistic regression; Dermatology Life Quality Index; Odds ratio; Body mass index; Severity of illness; Confidence interval; Gastroenterology; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00359939,0.0002563672,0.001093779,0.0003467223,0.0001464274,0.000470878,0.000243676,0.0003593956,0.001175515],"category_scores_gemma":[0.002903068,0.000217137,0.00221126,0.0004258326,0.0002088889,0.000315528,0.000305268,0.0005462921,0.00009760915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001457087,"about_ca_system_score_gemma":0.000281459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002267012,"about_ca_topic_score_gemma":0.0004969555,"domain_scores_codex":[0.9985701,0.0009296123,0.0001217142,0.0001689899,0.000124298,0.00008534284],"domain_scores_gemma":[0.9960213,0.002191559,0.001220505,0.000166653,0.00009855688,0.0003014256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0566603,0.0003668932,0.9198361,0.0002879828,0.003984109,0.0001022074,0.00007824188,0.0004783629,0.001889748,0.00004067913,0.0002371088,0.01603828],"study_design_scores_gemma":[0.002454144,0.01144875,0.9794392,0.00006850875,0.003252703,0.0004418629,0.0001028097,0.001587696,0.000613944,0.0001149908,0.0004584022,0.00001685862],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976867,0.001831467,0.0001337757,0.00003810999,0.000008196605,0.0000278883,0.00007333112,0.000003782039,0.0001967517],"genre_scores_gemma":[0.9996133,0.0001560721,0.0000752956,0.0000188481,0.00001377114,0.00001163269,0.00007514424,9.508376e-7,0.00003489786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00359939,"threshold_uncertainty_score":0.01903564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0145950923511643,"score_gpt":0.2401291534188116,"score_spread":0.2255340610676473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}