{"id":"W4289594701","doi":"10.1111/jdv.18474","title":"Super‐response to guselkumab treatment in patients with moderate‐to‐severe psoriasis: age, body weight, baseline Psoriasis Area and Severity Index, and baseline Investigator's Global Assessment scores predict complete skin clearance","year":2022,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Janssen Research and Development","keywords":"Medicine; Psoriasis Area and Severity Index; Psoriasis; Internal medicine; Logistic regression; Dermatology Life Quality Index; Odds ratio; Body mass index; Severity of illness; Confidence interval; Gastroenterology; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009852361,0.0003575659,0.0008598084,0.000274719,0.0003623281,0.00001207487,0.0003561116,0.0001729867,0.00003217516],"category_scores_gemma":[0.0001782662,0.0002494183,0.00008754986,0.0002816263,0.0004308696,0.0001056396,0.0004192769,0.0004899487,0.000002438092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001244939,"about_ca_system_score_gemma":0.0001459066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003390474,"about_ca_topic_score_gemma":0.000033784,"domain_scores_codex":[0.9930128,0.005295964,0.0007521119,0.0004193544,0.0001245629,0.0003952163],"domain_scores_gemma":[0.9987119,0.0004242427,0.0004348682,0.0001979415,0.00006529107,0.0001657145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01909999,0.0005313317,0.9712222,0.0000270739,0.0007147619,0.0001571659,0.0006206072,0.0003447286,0.0008467464,0.0001365791,0.001268755,0.005030128],"study_design_scores_gemma":[0.01167217,0.0008473542,0.9773604,0.00007530946,0.0003230572,0.002272795,0.0001255456,0.000082983,0.0005201551,0.0001729757,0.006297354,0.0002499092],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928045,0.001519876,0.00007120075,0.004494176,0.0003188276,0.000433603,0.0003038122,0.00001278361,0.00004123936],"genre_scores_gemma":[0.9979405,0.0002502924,0.0005181561,0.001134614,0.0000425304,0.0000201126,0.00002203985,0.00002344548,0.00004834492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007427816,"threshold_uncertainty_score":0.9999958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0145950923511643,"score_gpt":0.2401291534188116,"score_spread":0.2255340610676473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}