{"id":"W4289687832","doi":"10.1186/s41512-022-00128-8","title":"Development and validation of prognostic models for anal cancer outcomes using distributed learning: protocol for the international multi-centre atomCAT2 study","year":2022,"lang":"en","type":"article","venue":"Diagnostic and Prognostic Research","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Hanarth Fonds; Yorkshire Cancer Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Academy of Medical Sciences; National Institute for Health and Care Research; Cancer Research UK","keywords":"Anal cancer; Medicine; Protocol (science); Chemoradiotherapy; Cohort; Cancer; Medical physics; Oncology; Internal medicine; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1149778,0.003107831,0.002827977,0.001664314,0.002345216,0.002670928,0.004305232,0.00426291,0.04184592],"category_scores_gemma":[0.121916,0.001884273,0.006089825,0.001908619,0.003408134,0.001934995,0.004953322,0.004033566,0.01169136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003981001,"about_ca_system_score_gemma":0.01890141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002094804,"about_ca_topic_score_gemma":0.002648188,"domain_scores_codex":[0.9540247,0.03326467,0.004243539,0.002856815,0.003963743,0.001646575],"domain_scores_gemma":[0.9145806,0.02823893,0.009816874,0.02351316,0.02025505,0.003595342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.2971704,0.02372994,0.02094877,0.06623687,0.006856885,0.003114171,0.006658621,0.05877073,0.01339813,0.02949573,0.1979693,0.2756504],"study_design_scores_gemma":[0.1927071,0.0671453,0.04274578,0.03187105,0.005057148,0.001153767,0.002275125,0.02761475,0.02147325,0.03169628,0.5752054,0.001055067],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01082462,0.0004486348,0.03617249,0.0006539712,0.000449575,0.9327114,0.0151591,0.0004225902,0.003157626],"genre_scores_gemma":[0.005645096,0.00009956877,0.01225664,0.0001461569,0.00002454737,0.9792084,0.002236588,0.00003188551,0.0003511105],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.1149778,"threshold_uncertainty_score":0.6080679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2686412484875302,"score_gpt":0.4606682543416242,"score_spread":0.192027005854094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}