{"id":"W4289687832","doi":"10.1186/s41512-022-00128-8","title":"Development and validation of prognostic models for anal cancer outcomes using distributed learning: protocol for the international multi-centre atomCAT2 study","year":2022,"lang":"en","type":"article","venue":"Diagnostic and Prognostic Research","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Hanarth Fonds; Yorkshire Cancer Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Academy of Medical Sciences; National Institute for Health and Care Research; Cancer Research UK","keywords":"Anal cancer; Medicine; Protocol (science); Chemoradiotherapy; Cohort; Cancer; Medical physics; Oncology; Internal medicine; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001298939,0.0001402031,0.0002539443,0.0001422017,0.0006775318,0.00005840058,0.0001404346,0.00003172929,0.00003855804],"category_scores_gemma":[0.004498575,0.0000964288,0.00005510207,0.0002411208,0.0001176721,0.00005897483,0.000295749,0.0002691108,2.084382e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143334,"about_ca_system_score_gemma":0.000384886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001389377,"about_ca_topic_score_gemma":0.0000418801,"domain_scores_codex":[0.9982216,0.0001333923,0.0003465606,0.0003380318,0.00064527,0.0003151107],"domain_scores_gemma":[0.9933711,0.005752738,0.0001058731,0.00009891371,0.0005659456,0.000105445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007384362,0.0009701526,0.9867564,0.0003213453,0.000211744,0.00001096139,0.002122807,0.001128757,0.00007445303,0.0001621804,0.000113325,0.007389478],"study_design_scores_gemma":[0.0102657,0.002270959,0.6847041,0.0002746289,0.0003451508,0.0000238773,0.01281898,0.2825813,0.0007631777,0.0003611314,0.005320733,0.0002702338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8966342,0.0001101493,0.003183246,0.0008585232,0.00004975302,0.09903071,0.000110256,0.00001585577,0.000007274154],"genre_scores_gemma":[0.8248593,0.00000503064,0.0008230872,0.00001699158,0.00004385418,0.1740277,0.00008903736,0.00001646826,0.0001185714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3020523,"threshold_uncertainty_score":0.538554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2686412484875302,"score_gpt":0.4606682543416242,"score_spread":0.192027005854094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}