{"id":"W4289710771","doi":"10.1097/med.0000000000000418","title":"β Cell replacement: improving on the design","year":2018,"lang":"en","type":"review","venue":"Current Opinion in Endocrinology Diabetes and Obesity","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Induced pluripotent stem cell; Cell therapy; Stem cell; Immune system; Medicine; Transplantation; Autoimmunity; Stem-cell therapy; Immunology; Bioinformatics; Biology; Embryonic stem cell; Cell biology; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009941729,0.0008387475,0.0012465,0.001247447,0.000227821,0.001168195,0.0009125394,0.001227306,0.003869391],"category_scores_gemma":[0.00121276,0.0003502791,0.0005133966,0.001024797,0.0005429599,0.001884758,0.0006885647,0.002059563,0.003116072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004886968,"about_ca_system_score_gemma":0.0009159623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005804252,"about_ca_topic_score_gemma":0.0005143086,"domain_scores_codex":[0.9996293,0.00006356368,0.00006017268,0.00007603623,0.000142031,0.00002884582],"domain_scores_gemma":[0.9995099,0.0002485051,0.00006612104,0.00002449381,0.0001223334,0.00002856268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006260138,0.0000474332,0.00018053,0.02622483,0.00006515744,0.000253016,0.00008512002,0.0005732895,0.006896764,0.01106709,0.01994199,0.9346022],"study_design_scores_gemma":[0.000009346244,0.00006574522,0.0002402737,0.002928535,0.00006924682,0.0009539704,0.00004055056,0.0001063915,0.001791499,0.002059113,0.9917203,0.00001511722],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001750251,0.9970993,0.0006399784,0.0004150752,0.0003703955,0.000007656665,0.00001607164,0.00001015186,0.001266484],"genre_scores_gemma":[0.00119622,0.9967039,0.0007993451,0.0003272017,0.0002809706,0.00001309874,0.00003389814,0.000004996686,0.0006403498],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003869391,"threshold_uncertainty_score":0.0129444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1042890241663428,"score_gpt":0.3463330168335655,"score_spread":0.2420439926672227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}