{"id":"W4289847450","doi":"10.21203/rs.3.rs-1911437/v1","title":"CaSR modulates proliferation of the superficial zone cells in temporomandibular joint cartilage via the PTHrP nuclear localization sequence","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; McGill University; Yale University","keywords":"Cartilage; Parathyroid hormone-related protein; Agonist; Receptor; Endocrinology; Chemistry; Internal medicine; Knockout mouse; Medicine; Parathyroid hormone; Anatomy; Calcium","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572687,0.0002658736,0.0002932903,0.0002559952,0.0002474911,0.0005763834,0.0003527655,0.0003607521,0.00382408],"category_scores_gemma":[0.0003477994,0.0001958944,0.0002974841,0.0001373097,0.0004833503,0.0003217701,0.0002619882,0.0006693699,0.0008027385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004841409,"about_ca_system_score_gemma":0.0002739964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502804,"about_ca_topic_score_gemma":0.001371247,"domain_scores_codex":[0.9998108,0.00002432008,0.0000116886,0.00006011047,0.0000414164,0.00005184792],"domain_scores_gemma":[0.9998204,0.00004203156,0.00004529785,0.00002510281,0.00001678988,0.00005037442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002136471,0.00000814354,0.00007330843,0.00003035618,0.000002554447,0.0000548814,0.00001301548,0.00002830152,0.9984611,0.0001542892,0.00005069643,0.00090976],"study_design_scores_gemma":[0.00005128116,0.0001618187,0.006314339,0.000006070801,0.00002115132,0.0003081909,0.00005095726,0.0009035919,0.9896401,0.0001342995,0.00239944,0.000008722783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881023,0.002825241,0.003731563,0.0002512694,0.0001249719,0.00001809906,0.0004347052,0.0002329849,0.004278889],"genre_scores_gemma":[0.9924044,0.0004610316,0.001455462,0.00005238732,0.00002485697,0.00001574461,0.0003686397,0.00007125436,0.005146223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00382408,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03850454126552651,"score_gpt":0.3253558820125023,"score_spread":0.2868513407469758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}