{"id":"W4289878735","doi":"10.1093/noajnl/vdac078.002","title":"BSCI-02 CSF PROTEOMICS AS A MINIMALLY-INVASIVE STRATEGY FOR DISTINGUISHING BRAIN METASTASES FROM OTHER PRIMARY BRAIN MALIGNANCIES","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Brain biopsy; Medicine; Cerebrospinal fluid; Brain tumor; Liquid biopsy; Proteomics; Malignancy; Biopsy; Oncology; Pathology; Cancer; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003516998,0.000338828,0.0007313427,0.0001360982,0.0004541185,0.00004453845,0.0002368678,0.00008810883,0.0004278826],"category_scores_gemma":[0.002753135,0.0003017532,0.0002263719,0.0002152527,0.0001906669,0.0001991491,0.0001881011,0.0003015165,0.00001579001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002959093,"about_ca_system_score_gemma":0.0005749394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001714777,"about_ca_topic_score_gemma":0.0003228514,"domain_scores_codex":[0.9975949,0.0003457654,0.0004641188,0.0007483875,0.0003336791,0.0005131718],"domain_scores_gemma":[0.993484,0.005520444,0.0003755182,0.0003449187,0.000116573,0.0001585576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003896088,0.003345936,0.03127404,0.0003225755,0.0007122962,0.004185201,0.001651557,0.001028365,0.8723245,0.002400652,0.04028028,0.03857848],"study_design_scores_gemma":[0.01150485,0.01318363,0.01146017,0.0001288732,0.0007162141,0.000567654,0.0035208,0.00009151285,0.1588441,0.008151967,0.7911345,0.0006957083],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729496,0.004252487,0.00009551024,0.01649038,0.000557175,0.002408414,0.001114391,0.0001375789,0.001994438],"genre_scores_gemma":[0.9420285,0.0002205289,0.01695534,0.03373931,0.0006498917,0.005182954,0.0006738595,0.0001378684,0.000411768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7508542,"threshold_uncertainty_score":0.9999434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02866664046053254,"score_gpt":0.3149593583259258,"score_spread":0.2862927178653933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}