{"id":"W4289878735","doi":"10.1093/noajnl/vdac078.002","title":"BSCI-02 CSF PROTEOMICS AS A MINIMALLY-INVASIVE STRATEGY FOR DISTINGUISHING BRAIN METASTASES FROM OTHER PRIMARY BRAIN MALIGNANCIES","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Brain biopsy; Medicine; Cerebrospinal fluid; Brain tumor; Liquid biopsy; Proteomics; Malignancy; Biopsy; Oncology; Pathology; Cancer; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006737332,0.0004863977,0.0003712316,0.001811563,0.000398435,0.001137647,0.0003089563,0.0004744371,0.001503633],"category_scores_gemma":[0.001271506,0.0001462074,0.000282581,0.0007856955,0.0002947053,0.0003438595,0.0005044148,0.000435345,0.0008388858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004489254,"about_ca_system_score_gemma":0.000456804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454228,"about_ca_topic_score_gemma":0.002531276,"domain_scores_codex":[0.9996734,0.0000448312,0.00003481323,0.00008317036,0.0001119972,0.00005184209],"domain_scores_gemma":[0.9994954,0.0001084664,0.0001070712,0.00003818538,0.0001701766,0.00008063256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001416445,0.0001628176,0.3351917,0.0003683134,0.0001607718,0.001191937,0.0001617779,0.0008755684,0.5658365,0.0002837651,0.004243569,0.09010677],"study_design_scores_gemma":[0.00007087298,0.0007962811,0.6320887,0.0001267072,0.0002256884,0.007358506,0.000433305,0.01832063,0.3279389,0.001100879,0.01148751,0.00005197942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819486,0.002636176,0.008712723,0.0004509396,0.00007287025,0.0001403747,0.003184929,0.0004050462,0.002448352],"genre_scores_gemma":[0.9805704,0.0006804955,0.01358322,0.0002286204,0.00005756048,0.0001079718,0.003856744,0.00004485505,0.0008702018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001811563,"threshold_uncertainty_score":0.005030215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02866664046053254,"score_gpt":0.3149593583259258,"score_spread":0.2862927178653933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}