{"id":"W4290190465","doi":"10.1007/s13555-022-00764-4","title":"Durability of Response to Abrocitinib in Patients with Moderate-to-Severe Atopic Dermatitis After Treatment Discontinuation in a Phase 2b Trial","year":2022,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada); SKiN Health","funders":"Pfizer","keywords":"Eczema Area and Severity Index; Discontinuation; Medicine; Atopic dermatitis; Placebo; Internal medicine; SCORAD; Gastroenterology; Dermatology; Disease; Dermatology Life Quality Index; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106022,0.0001350262,0.0004428848,0.000231092,0.00005861567,0.000004499167,0.00004140937,0.0000615805,0.0001346977],"category_scores_gemma":[0.00004056705,0.0001078907,0.00003829387,0.0002027068,0.00006386923,0.00006113343,0.00002341786,0.00009686232,0.000002404748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005474191,"about_ca_system_score_gemma":0.0000919157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002175578,"about_ca_topic_score_gemma":0.00005763839,"domain_scores_codex":[0.9986318,0.00048628,0.0003429069,0.000239084,0.0001152743,0.0001846605],"domain_scores_gemma":[0.9994922,0.0001424035,0.00006001693,0.0001883649,0.00003215049,0.0000849206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.314946,0.002163276,0.6779175,0.00001091624,0.00003879984,0.0001893909,0.001926193,0.0000136667,0.00001271263,0.00001787856,0.00004889049,0.002714799],"study_design_scores_gemma":[0.1186478,0.001772422,0.8779354,0.00002346306,0.00001522642,0.00007401072,0.0001290764,0.00003505951,0.0003375766,0.0001414879,0.0007845905,0.0001038868],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957739,0.0002536409,0.00001476746,0.002288002,0.00004950051,0.0015199,0.00005765996,0.0000120504,0.00003056568],"genre_scores_gemma":[0.9976203,0.00001975161,0.00005281005,0.001434912,0.000004859989,0.0007846692,0.00005094922,0.000008995454,0.00002278437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2000179,"threshold_uncertainty_score":0.4399656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116380970342414,"score_gpt":0.2820543683081328,"score_spread":0.2708905586047087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}